{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T23:07:45Z","timestamp":1785366465839,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This retrospective, methods comparison study aimed to compare skeletal scintigraphy and <jats:sup>18<\/jats:sup>F\u2010NaF positron emission tomography (PET) for the detection of abnormalities in the fetlocks of Thoroughbred racehorses. Thirty\u2010three horses (72 limbs) imaged with both scintigraphy and <jats:sup>18<\/jats:sup>F\u2010NaF PET, for investigation of lameness or poor performance related to the fetlock, were included. Seven observers, including experienced racetrack practitioners, surgery and imaging residents, and a board\u2010certified veterinary radiologist, independently reviewed all data for evidence of increased radiopharmaceutical uptake in 10 different regions of interest. The interobserver agreement was higher for PET (Kappa\u2010weighted (K\u2010w) 0.73 (0.51\u20130.84)) (median (range)) than for scintigraphy (0.61 (0.40\u20130.77)) (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001). When scintigraphy and PET were compared, the agreement was fair (K\u2010w 0.29). More sites of increased uptake were identified using PET compared with scintigraphy. Agreement between the two modalities was higher for the palmar\/plantar metacarpal\/metatarsal condylar regions (K\u2010w 0.59) than for the proximal sesamoid bones (K\u2010w 0.25). Increased radiopharmaceutical uptake was detected in the medial proximal sesamoid bone in 6.9% and 22.2% of limbs with scintigraphy and PET, respectively. The high interobserver agreement for PET, despite the recent introduction of this technique, demonstrates the ease of clinical interpretation of PET scans. The higher number of lesions detected with PET compared with scintigraphy can be explained by the higher spatial resolution and cross\u2010sectional nature of this modality. Study findings supported using PET in a clinical population of racehorses, in particular for the assessment of the proximal sesamoid bones.<\/jats:p>","DOI":"10.1111\/vru.13169","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T11:44:52Z","timestamp":1666007092000},"page":"123-130","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Comparison of skeletal scintigraphy and standing <sup>18<\/sup>F\u2010NaF positron emission tomography for imaging of the fetlock in 33 Thoroughbred racehorses"],"prefix":"10.1111","volume":"64","author":[{"given":"Mathieu","family":"Spriet","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine University of California, Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Arndt","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine University of California, Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlene","family":"Pige","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine University of California, Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jannah","family":"Pye","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine University of California, Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"O'Brion","sequence":"additional","affiliation":[{"name":"Southern California Equine Foundation  Arcadia California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Carpenter","sequence":"additional","affiliation":[{"name":"Southern California Equine Foundation  Arcadia California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeff","family":"Blea","sequence":"additional","affiliation":[{"name":"Southern California Equine Foundation  Arcadia California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph P.","family":"Dowd","sequence":"additional","affiliation":[{"name":"Southern California Equine Foundation  Arcadia California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2002.tb05424.x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cveq.2012.09.005"},{"key":"e_1_2_11_4_1","first-page":"151","volume-title":"Equine Scintigraphy","author":"Martinelli MJ","year":"2003"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2010.00088.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12719"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12430"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13019"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.13078"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.2307\/2529310"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13299"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.13001"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516409X368372"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13414"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/1040638717717948"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12512"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.246.6.661"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2011.00389.x"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2010.00316.x"},{"key":"e_1_2_11_20_1","volume-title":"California Horse Racing Board Postmortem Examination Program 2017\u20132018 Annual Report (2019)","year":"2019"},{"key":"e_1_2_11_21_1","volume-title":"California Horse Racing Board Report on Fatalities at Santa Anita Park from 12\/30\/18 through 3\/31\/19","year":"2020"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.71.7.755"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13291"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13273"}],"container-title":["Veterinary Radiology &amp; 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