{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:37:41Z","timestamp":1762079861449,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T00:00:00Z","timestamp":1692576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of this retrospective, observational, controlled study was to evaluate bone and soft tissue window CT images of the proximoplantar metatarsus III region in twenty horses with pain localized to the proximal suspensory ligament (PSL) and 20 horses with findings nonrelated to tarsal pain. All horses underwent CT and radiographic examination. Images were reviewed by three independent observers who graded the severity and localization of findings. Bone\u2010related categories as well as soft tissue\u2010related categories were evaluated. For the comparison of imaging findings in horses with and without proximal suspensory desmitis (PSD), mixed linear regression was performed. The intraclass correlation coefficient (ICC) was calculated to assess intraobserver agreement, and kappa statistics were employed to evaluate interobserver agreement. CT examination identified significantly more abnormalities in the diseased group. The scores for osseous exostosis (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.015) and PSL enlargement (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.004) were notably higher in PSD horses compared to controls. Intraobserver agreement was overall high (ICC .82\u20131.0), and interobserver agreement was substantial for the detection of mineralization (kappa\u00a0=\u00a0.61) and moderate for sclerosis (kappa\u00a0=\u00a0.43), exostosis (kappa\u00a0=\u00a0.43), and PSL enlargement (kappa\u00a0=\u00a0.48\/.51). Measurements in the soft tissue window were significantly smaller than those in the bone window. Findings concurrent with PSD including osseous proliferation and sclerosis as well as soft tissue enlargement, mineralization, and avulsion can be reliably detected using CT. Findings from the current study supported the use of CT for evaluating horses with suspected PSD where high\u2010field MRI is not available.<\/jats:p>","DOI":"10.1111\/vru.13292","type":"journal-article","created":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T04:31:47Z","timestamp":1692678707000},"page":"1005-1014","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Findings consistent with equine proximal suspensory desmitis can be reliably detected using computed tomography and differ between affected horses and controls"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9523-6942","authenticated-orcid":false,"given":"Eva M. T.","family":"M\u00fcller","sequence":"first","affiliation":[{"name":"Equine Clinic, School of Veterinary Medicine Freie Universit\u00e4t Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrien","family":"Vanderperren","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging of Domestic Animals and Orthopedics of Small Animals, Faculty of Veterinary Medicine Ghent University  Merelbeke Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roswitha","family":"Merle","sequence":"additional","affiliation":[{"name":"Institute for Veterinary Epidemiology and Biostatistics, School of Veterinary Medicine Freie Universit\u00e4t Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svenja","family":"Rheinfeld","sequence":"additional","affiliation":[{"name":"Equine Clinic, School of Veterinary Medicine Freie Universit\u00e4t Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pitiporn","family":"Leelamankong","sequence":"additional","affiliation":[{"name":"Equine Clinic, School of Veterinary Medicine Freie Universit\u00e4t Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph J.","family":"Lischer","sequence":"additional","affiliation":[{"name":"Equine Clinic, School of Veterinary Medicine Freie Universit\u00e4t Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Ehrle","sequence":"additional","affiliation":[{"name":"Equine Clinic, School of Veterinary Medicine Freie Universit\u00e4t Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,21]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042\u20103292.2002.tb00137.x"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.12331"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.13187"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2008.00385.x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12563"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13562"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.3415\/VCOT\u201013\u201012\u20100146"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.5167\/uzh\u2010100034"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042\u20103306.2012.00597.x"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516406X156109"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740\u20108261.2009.01614.x"},{"key":"e_1_2_12_13_1","first-page":"714423","volume-title":"Magnetic resonance imaging findings of the proximal metacarpal region in warmblood horses: 36 lame and 26 control limbs (2015\u20102021)","author":"Veggel E","year":"2021"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12659"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740\u20108261.2011.01922.x"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12756"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042\u20103306.2011.00386.x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.12885"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.13182"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.13388"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.13290"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.21.10.0439"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.234.4.514"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.2307\/2529310"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042\u20103292.2003.tb00231.x"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.245.10.1153"}],"container-title":["Veterinary Radiology &amp; 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