{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T02:58:50Z","timestamp":1775098730613,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T00:00:00Z","timestamp":1712966400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hyperadrenocorticism is an uncommon but important endocrine disease in guinea pigs, but due to its subtle clinical signs and the limited information in veterinary literature, it can be underdiagnosed or misdiagnosed. Ultrasound of the adrenal glands in patients with suspected hyperadrenocorticism can help in identifying adrenomegaly. The purpose of this prospective study was to identify ultrasonographic adrenal gland dimensions in presumed healthy guinea pigs using the same standardized method described for dogs and cats. A conscious ultrasound scan was conducted on twenty client\u2010owned, presumed healthy guinea pigs, and their adrenal glands were measured. A possible correlation between adrenal dimensions with age, sex, and body weight was investigated. The mean length, cranial and caudal pole thickness for the left and right adrenal glands were, respectively, 12.64\u00a0\u00b1\u00a02.11\u00a0mm and 11.55\u00a0\u00b1\u00a01.52\u00a0mm; 4.83\u00a0mm\u00a0\u00b1\u00a01.03\u00a0mm and 4.69\u00a0\u00b1\u00a01.34\u00a0mm; 4.8\u00a0\u00b1\u00a01.23\u00a0mm and 4.04\u00a0\u00b1\u00a00.75\u00a0mm. The thickness of the left caudal pole was significantly higher than the right (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.02). A significant positive correlation was found between the length of the left adrenal gland and both age (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.46; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.03) and weight (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.59; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.01). Statistical correlation between the thickness of each cranial and caudal pole, with age, sex, or weight, was not found. The dimensions provided could prove a useful tool in the clinical evaluation of guinea pigs with suspected hyperadrenocorticism.<\/jats:p>","DOI":"10.1111\/vru.13367","type":"journal-article","created":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T15:05:25Z","timestamp":1713020725000},"page":"385-391","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Ultrasonographic measurements of the normal adrenal glands in guinea pigs <i>(Cavia Porcellus)<\/i>"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2585-4059","authenticated-orcid":false,"given":"Domenico","family":"Sainato","sequence":"first","affiliation":[{"name":"Eastcott Referrals, Edison Business Park  Swindon UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7896-2053","authenticated-orcid":false,"given":"Tina","family":"Pelligra","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences University of Pisa  San Piero a Grado Pisa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5313-0621","authenticated-orcid":false,"given":"Caterina","family":"Puccinelli","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences University of Pisa  San Piero a Grado Pisa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Petrini","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences University of Pisa  San Piero a Grado Pisa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8211-9248","authenticated-orcid":false,"given":"Simonetta","family":"Citi","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences University of Pisa  San Piero a Grado Pisa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,13]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"The biology of the guinea pig","author":"Wagner JE","year":"1976"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jepm.2020.03.010"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2015.08.016"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anicom.2012.11.001"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12122"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2010.05.009"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2013.01.001"},{"key":"e_1_2_11_9_1","first-page":"211","volume-title":"The biology of the Guinea Pig","author":"Manning PJ","year":"1984"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02275339"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1158\/ajc.1940.310"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1962.80"},{"key":"e_1_2_11_13_1","first-page":"2583","article-title":"Susceptibility of guinea pigs to chemical carcinogens: 7,12\u2010dimethylbenz(a)anthrene and urethan","volume":"30","author":"Toth B","year":"1970","journal-title":"Cancer Res"},{"key":"e_1_2_11_14_1","first-page":"377","article-title":"Erkrankungen des meerschweinchens aus sicht der pathologie","volume":"32","author":"Sommerey CC","year":"2004","journal-title":"Tier\u00e4rztliche Praxis"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740\u20108261.1998.tb00323.x"},{"key":"e_1_2_11_16_1","volume-title":"Hyperadrenokortizismus beim Meerschweinchen. (Thesis)","author":"Nowotny I","year":"2010"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.160.25.878"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12192"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.30539\/iraqijvm.v43i1.475"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12298"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X20979509"},{"key":"e_1_2_11_22_1","volume-title":"Anatomy of the Guinea Pig","author":"Cooper G","year":"1975"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo\u201032\u20103\u2010298"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X2097496"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1963.sp007262"},{"key":"e_1_2_11_26_1","volume-title":"Diagnostic Imaging in exotic pets","author":"Krautwald\u2010Junghanns ME","year":"2010"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00580\u2010014\u20102034\u20103"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/vetr.3668"}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.13367","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T05:39:27Z","timestamp":1721367567000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vru.13367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,13]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1111\/vru.13367"],"URL":"https:\/\/doi.org\/10.1111\/vru.13367","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"value":"1058-8183","type":"print"},{"value":"1740-8261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,13]]},"assertion":[{"value":"2023-10-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}