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We explored a new approach to evaluate the feasibility and reproducibility of RIOM during RT with five total client\u2010owned tumor\u2010bearing animals using a remote\u2010triggered breath\u2010hold ventilator under general anesthesia during image acquisition and RT. There was one stereotactic body radiotherapy, one conventionally fractionated definitive intent, and three conventionally fractionated palliative intent RT cases. Based on repeated cone beam CT, there were no treatment table shifts required prior to initiating beam on. No clinically significant complications such as hypotension occurred during anesthesia. This technique appeared to be safe in this group of patients and was easily clinically implemented and highly reproducible. More complete follow\u2010up data and larger studies are needed to evaluate clinical outcomes with this breath\u2010hold ventilator technique in veterinary RT.<\/jats:p>","DOI":"10.1111\/vru.13412","type":"journal-article","created":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T08:19:18Z","timestamp":1721031558000},"page":"672-678","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Feasibility assessment of inspiration breath\u2010hold motion management for tumor tracking during cone\u2010beam computed tomography for setup and radiotherapy in Veterinary Medicine: A pilot study"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9755-5501","authenticated-orcid":false,"given":"Keiko","family":"Murakami","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences Iowa State University College of Veterinary Medicine  Ames Iowa USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4884-0933","authenticated-orcid":false,"given":"Nicholas","family":"Rancilio","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences Iowa State University College of Veterinary Medicine  Ames Iowa USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Foster","sequence":"additional","affiliation":[{"name":"Lloyd Veterinary Medical Center Iowa State University College of Veterinary Medicine  Ames Iowa USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01453-5"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/jmp.JMP_22_17"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2011.01838.x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2012.01986.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12198"},{"issue":"1","key":"e_1_2_11_7_1","first-page":"95","article-title":"Stereotactic radiation therapy in veterinary medicine","volume":"56","author":"Bloomfield R","year":"2015","journal-title":"Can Vet J"},{"issue":"23","key":"e_1_2_11_8_1","first-page":"00177","article-title":"Update in veterinary radiation oncology: focus on stereotactic radiation therapy","volume":"0195","author":"Nolan MW","year":"2023","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(00)01370-5"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.meddos.2005.12.002"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canrad.2006.05.009"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vco.12928"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2018.04.001"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2020.01.002"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2006.11.012"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/acm2.12887"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.250.2.199"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/vco.12032"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00045413-199901000-00006"}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.13412","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T09:12:21Z","timestamp":1731143541000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vru.13412"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,15]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1111\/vru.13412"],"URL":"https:\/\/doi.org\/10.1111\/vru.13412","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"value":"1058-8183","type":"print"},{"value":"1740-8261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,15]]},"assertion":[{"value":"2024-02-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}