{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T22:42:49Z","timestamp":1789684969833,"version":"4.0.1"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T00:00:00Z","timestamp":1734307200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T00:00:00Z","timestamp":1734307200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Soft tissue sarcomas (STSs) constitute a heterogeneous group of tumors that originate from mesenchymal cells. Imaging plays an important role in the assessment of the oncological stage of STSs. Computed tomography findings facilitate the identification of the tumor location and margins in relation to the surrounding anatomic boundaries and thereby enable preoperative planning of tumor management. The histological grade is among the most important parameters that affect tumor recurrence and metastasis rates. However, the prediction of STS histological grades using CT characteristics has not yet been elucidated. This study retrospectively investigated CT findings of patients with different STS grades for differentiation. Thirty dogs with STSs (12 Grade 1, 10 Grade 2, and 8 Grade 3) were included from three animal hospitals. The investigated CT features included tumor delineation, dysmorphic intratumoral or peritumoral vessels, contrast enhancement patterns, peripheral rim enhancement, intratumoral calcification, degree of intratumoral cystic lesions, peritumoral fat stranding, metastatic regional lymphadenopathy, and lung metastasis. Quantitative findings included tumor size and pre\u2010 and postcontrast attenuation. Tumor size, dysmorphic intratumoral or peritumoral vessels, peritumoral fat stranding, and metastatic regional lymphadenopathy significantly differed among tumor grades. On post hoc analysis, Grade 3 tumors were significantly larger, had a higher prevalence of dysmorphic vessels than Grade 1 tumors, and had a significantly higher rate of adjacent metastatic lymphadenopathy than Grade 2 tumors. Predicting STS grades before the histopathological examination could potentially aid in the planning of the STS resection margins.<\/jats:p>","DOI":"10.1111\/vru.13478","type":"journal-article","created":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T23:35:02Z","timestamp":1734392102000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Usefulness of computed tomography findings for predicting soft tissue sarcoma grades"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4736-7099","authenticated-orcid":false,"given":"Jeongyun","family":"Jeong","sequence":"first","affiliation":[{"name":"Department of Veterinary Medical Imaging College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0695-3430","authenticated-orcid":false,"given":"Myounghun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medical Imaging College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jongwon","family":"Koo","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medical Imaging College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yewon","family":"Joo","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medical Imaging College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heejung","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medical Imaging College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minjoo","family":"Kim","sequence":"additional","affiliation":[{"name":"Shine Animal Medical Center Ogeum\u2010ro  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jungmin","family":"Kwak","sequence":"additional","affiliation":[{"name":"Human &amp; Animal Medical Center  Yongin Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5728-4820","authenticated-orcid":false,"given":"Jaehwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medical Imaging College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7989-0939","authenticated-orcid":false,"given":"Kidong","family":"Eom","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medical Imaging College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12556"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300985810388820"},{"key":"e_1_2_10_4_1","first-page":"404","volume-title":"Withrow & MacEwen's Small Animal Clinical Oncology","author":"Liptak JM","year":"2020"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.5326\/0410241"},{"key":"e_1_2_10_6_1","first-page":"52","article-title":"Review: biology of mesenchymal tumors","volume":"7","author":"Duda RB","year":"1994","journal-title":"Cancer J"},{"key":"e_1_2_10_7_1","first-page":"173","article-title":"Soft\u2010tissue sarcomas","volume":"10","author":"Thrall DE","year":"1995","journal-title":"Semin Vet Med Surg Small Anim"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1997.211.09.1147"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.08\u2010VP\u20100277\u2010M\u2010FL"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2014.12185.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.228.7.1053"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086\u2010200201000\u201000024"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12807"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2008.00408.x"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748\u20105827.2009.00809.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1096\u20102867(98)80029\u20107"},{"issue":"11","key":"e_1_2_10_17_1","first-page":"1048","article-title":"Soft tissue sarcomas in dogs","volume":"46","author":"Mayer MN","year":"2005","journal-title":"Can Vet J"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1989.194.01.60"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910330108"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1990.196.11.1795"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12178"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2019181659"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2019.08.059"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2019.08.008"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2024.111548"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2009.07.019"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300985813503565"},{"issue":"11","key":"e_1_2_10_28_1","first-page":"1209","article-title":"Factors influencing complete tumor excision of mast cell tumors and soft tissue sarcomas: a retrospective study in 100 dogs","volume":"52","author":"Monteiro B","year":"2011","journal-title":"Can Vet J"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.43\u20105\u2010622"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197111182852108"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1206813"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0959\u20108049(96)00379\u20106"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600315"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/01652176.2005.9695186"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102559.2005.02142.x"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1054\/bjoc.2001.1837"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.227.1442"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.258.2.179"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476\u20105829.2012.00333.x"}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.13478","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vru.13478","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.13478","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:54:21Z","timestamp":1773010461000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vru.13478"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,16]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1111\/vru.13478"],"URL":"https:\/\/doi.org\/10.1111\/vru.13478","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"value":"1058-8183","type":"print"},{"value":"1740-8261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,16]]},"assertion":[{"value":"2024-08-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13478"}}