{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:17:33Z","timestamp":1790803053965,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>In this analytical cross\u2010sectional method comparison study, we evaluated brain MR images in 30 dogs and cats with and without using a DICOM\u2010based deep\u2010learning (DL) denoising algorithm developed specifically for veterinary patients. Quantitative comparison was performed by measuring signal\u2010to\u2010noise (SNR) and contrast\u2010to\u2010noise ratios (CNR) on the same T2\u2010weighted (T2W), T2\u2010FLAIR, and Gradient Echo (GRE) MR brain images in each patient (native images and after denoising) in identical regions of interest. Qualitative comparisons were then conducted: three experienced veterinary radiologists independently evaluated each patient's T2W, T2\u2010FLAIR, and GRE image series. Native and denoised images were evaluated separately, with observers blinded to the type of images they were assessing. For each image type (native and denoised) and pulse sequence type image, they assigned a subjective grade of coarseness, contrast, and overall quality. For all image series tested (T2W, T2\u2010FLAIR, and GRE), the SNRs of cortical gray matter, subcortical white matter, deep gray matter, and internal capsule were statistically significantly higher on images treated with DL denoising algorithm than native images. Similarly, for all image series types tested, the CNRs between cortical gray and white matter and between deep gray matter and internal capsule were significantly higher on DL algorithm\u2010treated images than native images. The qualitative analysis confirmed these results, with generally better coarseness, contrast, and overall quality scores for the images treated with the DL denoising algorithm. In this study, this DICOM\u2010based DL denoising algorithm reduced noise in 1.5T MRI canine and feline brain images, and radiologists\u2019 perceived image quality improved.<\/jats:p>","DOI":"10.1111\/vru.70015","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T05:45:12Z","timestamp":1739425512000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A Veterinary DICOM\u2010Based Deep Learning Denoising Algorithm Can Improve Subjective and Objective Brain MRI Image Quality"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9147-6079","authenticated-orcid":false,"given":"Wilfried","family":"Mai","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences and Advanced Medicine School of Veterinary Medicine University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8805-836X","authenticated-orcid":false,"given":"Silke","family":"Hecht","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine University of Tennessee  Knoxville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5138-3802","authenticated-orcid":false,"given":"Matthew","family":"Paek","sequence":"additional","affiliation":[{"name":"Synergy Veterinary Imaging Partners MD\/VA  Frederick Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4597-5875","authenticated-orcid":false,"given":"Shannon P.","family":"Holmes","sequence":"additional","affiliation":[{"name":"AXIS \u2013 Animal Cross\u2010Sectional Imaging Specialists  Sarasota Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0572-721X","authenticated-orcid":false,"given":"Hugo","family":"Dorez","sequence":"additional","affiliation":[{"name":"Hawkcell  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9851-1491","authenticated-orcid":false,"given":"Martin","family":"Blanchard","sequence":"additional","affiliation":[{"name":"Hawkcell  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1635-7250","authenticated-orcid":false,"given":"Jamil Nour","family":"Eddin","sequence":"additional","affiliation":[{"name":"Hawkcell  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.2174\/1573405613666170428154156"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-018-1638-2"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2017.12.026"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-83515-3"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2021.731936"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2021.721167"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12912"},{"key":"e_1_2_10_9_1","article-title":"A Review of Radiomics and Artificial Intelligence and Their Application in Veterinary Diagnostic Imaging","volume":"9","author":"Bouhali O.","year":"2022","journal-title":"Veterinary Science"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2024.105317"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2021.611556"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.13171"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.13163"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.13160"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.13159"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.13062"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12901"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12003"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/08987564231221071"},{"key":"e_1_2_10_20_1","article-title":"Artificial Intelligence in Veterinary Imaging: An Overview","volume":"10","author":"Pereira A. 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