{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:28:12Z","timestamp":1787758092485,"version":"build-2784847793"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:00:00Z","timestamp":1780617600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:00:00Z","timestamp":1780617600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>In female animals, the functional status of the ovary is closely associated with ovarian hemodynamics. Contrast\u2010enhanced ultrasonography (CEUS) is a noninvasive imaging technology that allows for the visualization of microvascular blood flow. However, there is a lack of research on the hemodynamics of rat ovaries. This study conducted CEUS dynamic monitoring of ovarian hemodynamics in rats during infancy and pregnancy, revealing significant variations in time\u2013intensity curve (TIC) parameters between the two periods. The findings demonstrate the ability of CEUS to quantitatively assess the hemodynamic characteristics of rat ovaries, indirectly indicating their functional status. Moreover, these results offer a technical method for the noninvasive monitoring of ovarian functional diseases by CEUS.<\/jats:p>","DOI":"10.1111\/vru.70132","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T07:07:12Z","timestamp":1780643232000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Quantitative Parameters of Contrast\u2010Enhanced Ultrasonography (CEUS) Monitoring Ovarian Hemodynamics in Rats"],"prefix":"10.1111","volume":"67","author":[{"given":"Zhijian","family":"Luo","sequence":"first","affiliation":[{"name":"The First School of Clinical Medicine Lanzhou University  Lanzhou People's Republic of China"},{"name":"Department of Ultrasound Affiliated Hospital of Southwest Medical University  Luzhou Sichuan Province People's Republic of China"},{"name":"The First Hospital of Lanzhou University  Lanzhou Gansu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Yang","sequence":"additional","affiliation":[{"name":"The First School of Clinical Medicine Lanzhou University  Lanzhou People's Republic of China"},{"name":"The First Hospital of Lanzhou University  Lanzhou Gansu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaorong","family":"Luo","sequence":"additional","affiliation":[{"name":"The First School of Clinical Medicine Lanzhou University  Lanzhou People's Republic of China"},{"name":"The First Hospital of Lanzhou University  Lanzhou Gansu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"The First School of Clinical Medicine Lanzhou University  Lanzhou People's Republic of China"},{"name":"The First Hospital of Lanzhou University  Lanzhou Gansu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyan","family":"Wang","sequence":"additional","affiliation":[{"name":"The First School of Clinical Medicine Lanzhou University  Lanzhou People's Republic of China"},{"name":"Key Laboratory for Reproductive Medicine and Embryo of Gansu Province  Lanzhou People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Ren","sequence":"additional","affiliation":[{"name":"The First School of Clinical Medicine Lanzhou University  Lanzhou People's Republic of China"},{"name":"The First Hospital of Lanzhou University  Lanzhou Gansu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Zhou","sequence":"additional","affiliation":[{"name":"The First School of Clinical Medicine Lanzhou University  Lanzhou People's Republic of China"},{"name":"The First Hospital of Lanzhou University  Lanzhou Gansu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5952-9094","authenticated-orcid":false,"given":"Xuehong","family":"Zhang","sequence":"additional","affiliation":[{"name":"The First School of Clinical Medicine Lanzhou University  Lanzhou People's Republic of China"},{"name":"The First Hospital of Lanzhou University  Lanzhou Gansu People's Republic of China"},{"name":"Key Laboratory for Reproductive Medicine and Embryo of Gansu Province  Lanzhou People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,5]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani13101615"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0000000000000733"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.2174\/157489011794578446"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsfs.2011.0026"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2021.07.013"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/rda.12059"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani12020210"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2021.08.010"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0178143"},{"issue":"3","key":"e_1_2_11_11_1","first-page":"137","article-title":"Reproductive Ultrasound of the Bitch and Queen","volume":"24","author":"Autumn P.","year":"2009","journal-title":"Topics in Companion Animal Medicine"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2021.106870"},{"key":"e_1_2_11_13_1","volume-title":"Ultrasound in Assisted Reproduction and Early Pregnancy","author":"Jane F.","year":"2021"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-018-1516-1"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3233\/CH-200842"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2022.10.009"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.11152\/mu-3577"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s42826-022-00112-9"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2014-1020"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3055"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2013.08.008"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1071\/RDv25n2_ED"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2005.05.001"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abi8683"},{"issue":"2","key":"e_1_2_11_25_1","first-page":"200","article-title":"Initial and Cyclic Recruitment of Ovarian Follicles","volume":"21","author":"Elizabeth A.","year":"2000","journal-title":"Endocrine Reviews"},{"key":"e_1_2_11_26_1","volume-title":"The Ovarian Innervation Participates in the Regulation of Ovarian Functions","author":"Roberto Dom\u00ednguez Sara E.","year":"2012"},{"key":"e_1_2_11_27_1","unstructured":"E.Sara The Ovarian Innervation Participates in the Regulation of Ovarian(LONGDOM 2011)."},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmt049"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep44810"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2023.1239681"},{"key":"e_1_2_11_31_1","article-title":"Ultrasonography in Experimental Reproductive Investigations on Rats","volume":"130","author":"Wang T.","year":"2017","journal-title":"Journal of Visualized Experiments"}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.70132","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vru.70132","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.70132","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:05:36Z","timestamp":1787756736000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vru.70132"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,5]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/vru.70132"],"URL":"https:\/\/doi.org\/10.1111\/vru.70132","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"value":"1058-8183","type":"print"},{"value":"1740-8261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,5]]},"assertion":[{"value":"2024-05-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70132"}}