{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T15:18:11Z","timestamp":1788016691651,"version":"build-2784847793"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T00:00:00Z","timestamp":1776643200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T00:00:00Z","timestamp":1776643200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Patent ductus arteriosus (PDA) is a common congenital heart defect in dogs, typically presenting as a left\u2010to\u2010right (L\u2013R) shunt. This multicenter retrospective study aimed to characterize thoracic radiographic changes in dogs with L\u2013R, right\u2010to\u2010left (R\u2013L), and bidirectional (BID) PDA. All dogs had an echocardiographic diagnosis of PDA and underwent thoracic radiography. Qualitative radiographic evaluations assessed left heart enlargement (LHE), right heart enlargement (RHE), main pulmonary artery dilation (MPAD), aortic dilation (AD), and lung patterns. Quantitative radiographic assessments included measurements of the vertebral heart score (VHS) and vertebral left atrial size (VLAS). A total of 22 dogs were included in the study (13 L\u2013R, 6 R\u2013L, and 3 BID). L\u2013R and BID shunts demonstrated a significantly higher prevalence of LHE (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.002) and lower prevalence of MPAD (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.002) compared to R\u2013L shunts, consistent with echocardiographic findings. All L\u2013R cases exhibited RHE on radiography, although echocardiography only revealed LHE. R\u2013L shunts were associated with a higher incidence of normal lung appearance compared to L\u2013R and BID shunts (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.018) and showed only RHE on radiographic evaluation. Finally, L\u2013R PDA displayed significantly higher VHS and VLAS compared to R\u2013L (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.01 and 0.03, respectively). In conclusion, this study provides a detailed characterization of the thoracic radiographic alterations associated with PDA, highlighting differences based on the type of shunt and their correlation with echocardiographic findings.\n                  <\/jats:p>","DOI":"10.1111\/vru.70164","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T12:13:55Z","timestamp":1776687235000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Radiographic Findings in Dogs With Patent Ductus Arteriosus: Left\u2010to\u2010Right, Right\u2010to\u2010Left, and Bidirectional Shunt"],"prefix":"10.1111","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5313-0621","authenticated-orcid":false,"given":"Caterina","family":"Puccinelli","sequence":"first","affiliation":[{"name":"Department of Veterinary Sciences University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Vezzosi","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oriol","family":"Domenech","sequence":"additional","affiliation":[{"name":"Anicura Istituto Veterinario Novara  Novara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edoardo","family":"Auriemma","sequence":"additional","affiliation":[{"name":"Anicura Istituto Veterinario Novara  Novara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Diana","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medical Sciences University of Bologna  Ozzano dell'Emilia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8449-9176","authenticated-orcid":false,"given":"Rosalba","family":"Tognetti","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simonetta","family":"Citi","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2011.0711.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2015.06.001"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0230160"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1760-2734(06)70010-8"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-141602398-2.10003-8"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000262481"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.16072"},{"issue":"21","key":"e_1_2_10_9_1","first-page":"1638","article-title":"Eisenmenger Syndrome: Diagnosis, Prognosis and Clinical Management","volume":"106","author":"Arvanitaki A.","year":"2020","journal-title":"British Medical Journal"},{"issue":"4","key":"e_1_2_10_10_1","first-page":"341","article-title":"Reference Values of M\u2010Mode Echocardiographic Parameters and Indices in Conscious Labrador Retriever Dogs","volume":"15","author":"Gugjoo M. 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