{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T22:30:14Z","timestamp":1778279414925,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T00:00:00Z","timestamp":1468195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To report the use of low\u2010pressure carbon dioxide insufflation during video\u2010assisted thoracoscopic surgery for resection of a noninvasive thymoma in a cat with secondary myasthenia gravis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Clinical case report.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animal<\/jats:title><jats:p>Client\u2010owned cat.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An 11\u2010year\u2010old castrated male domestic shorthair cat was examined for generalized weakness, voice change, hypersalivation, hyporexia, vomiting, coughing, and gagging. Thoracic ultrasound revealed a cranial mediastinal mass for which cytology was consistent with a thymoma (or lymphoid tissue). Acetylcholine receptor antibody concentration was elevated at 3.16 mmol\/L (reference interval\u2009&lt;\u20090.3 mmol\/L). Thoracic computed tomography showed two round, contrast\u2010enhancing structures in the cranioventral mediastinum identified as the sternal lymph node and a cranial mediastinal mass (11 \u00d7 17 \u00d7 24 mm). A presumptive diagnosis of thymoma with paraneoplastic myasthenia gravis was made and surgical resection of both mediastinal masses was recommended.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Video\u2010assisted thoracoscopic resection of the cranial mediastinal mass and sternal lymph node were performed with low\u2010pressure carbon dioxide insufflation maintained at an intrathoracic pressure of 2\u20133 mmHg. The cat recovered from surgery without serious complications. Nineteen months after surgery, the cat developed hind limb stiffness. Thoracic radiographs ruled out a cranial mediastinal mass or megaesophagus. Acetylcholine receptor antibody concentration remained elevated at 2.72 mmol\/L.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Low\u2010pressure thoracic insufflation facilitated video\u2010assisted thoracoscopic resection of cranial mediastinal masses in this cat.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.12504","type":"journal-article","created":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T12:55:28Z","timestamp":1468241728000},"source":"Crossref","is-referenced-by-count":15,"title":["Video\u2010Assisted Thoracoscopic Resection of a Noninvasive Thymoma in a Cat with Myasthenia Gravis Using Low\u2010Pressure Carbon Dioxide Insufflation"],"prefix":"10.1111","volume":"45","author":[{"given":"Maureen A.","family":"Griffin","sequence":"first","affiliation":[{"name":"Department of Surgical and Radiological Sciences, School of Veterinary Medicine University of California\u2010Davis Davis California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessie S.","family":"Sutton","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences, School of Veterinary Medicine University of California\u2010Davis Davis California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geraldine B.","family":"Hunt","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences, School of Veterinary Medicine University of California\u2010Davis Davis California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno H.","family":"Pypendop","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences, School of Veterinary Medicine University of California\u2010Davis Davis California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp D.","family":"Mayhew","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences, School of Veterinary Medicine University of California\u2010Davis Davis California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,7,11]]},"reference":[{"key":"e_1_2_5_2_1","volume-title":"Withrow & MacEwen's small animal clinical oncology","author":"Withrow SJ","year":"2013"},{"key":"e_1_2_5_3_1","first-page":"1355","article-title":"Clinical and pathological features of thymoma in 15 dogs","volume":"184","author":"Aronsohn MG","year":"1984","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1998.tb03734.x"},{"key":"e_1_2_5_5_1","volume-title":"Clinical medicine of the dog and cat","author":"Schaer M","year":"2010"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-4431.2008.00290.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2000.216.55"},{"key":"e_1_2_5_8_1","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.2460\/javma.1997.211.11.1428","article-title":"Risk factors for acquired myasthenia gravis in dogs: 1,154 cases (1991\u20131995)","volume":"211","author":"Shelton GD","year":"1997","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.232.8.1186"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2008.00447.x"},{"key":"e_1_2_5_11_1","first-page":"O115","article-title":"Video\u2010assisted thoracoscopic cranial mediastinal mass extirpation in dogs: 18 cases (2009\u20102014). 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