{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:31:18Z","timestamp":1740126678273,"version":"3.37.3"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T00:00:00Z","timestamp":1489968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Center for Companion Animal Health, School of Veterinary Medicine, University of California-Davis"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To improve the prediction of fractures in dogs with bone tumors of the distal radius by identifying computed tomography (CT) indices that correlate with antebrachial bone strength and fracture location.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Prospective experimental study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Dogs with antebrachial osteosarcoma (n\u2009=\u200910), and normal cadaver bones (n=9).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Antebrachia were imaged with quantitative CT prior to biomechanical testing to failure. CT indices of structural properties were compared to yield force and maximum force using Pearson correlation tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Straight beam failure (Fs), axial rigidity, curved beam failure (Fc), and craniocaudal bending moment of inertia (MOICrCd) CT indices most highly correlated (0.77\u2009&gt;\u2009R\u2009&gt;\u20090.57) with yield and maximum forces when iOSA\u2010affected and control bones were included in the analysis. Considering only OSA\u2010affected bones, Fs, Fc, and axial rigidity correlated highly (0.85\u2009&gt;\u2009R\u2009&gt;\u20090.80) with maximum force. In affected bones, the location of minimum axial rigidity and maximum MOICrCd correlated highly (R\u2009&gt;\u20090.85) with the actual fracture location.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CT\u2010derived axial rigidity, Fs, and MOICrCd have strong linear relationships with yield and maximum force. These indices should be further evaluated prospectively in OSA\u2010affected dogs that do, and do not, experience pathologic fracture.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.12645","type":"journal-article","created":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T15:16:50Z","timestamp":1490023010000},"page":"549-558","source":"Crossref","is-referenced-by-count":2,"title":["CT\u2010derived indices of canine osteosarcoma\u2010affected antebrachial strength"],"prefix":"10.1111","volume":"46","author":[{"given":"Tanya C.","family":"Garcia","sequence":"first","affiliation":[{"name":"Department of Anatomy, Physiology and Cell Biology Surgical, School of Veterinary Medicine University of California\u2014Davis Davis California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0852-0644","authenticated-orcid":false,"given":"Michele A.","family":"Steffey","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences, 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