{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:14:21Z","timestamp":1791976461303,"version":"4.4.0"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T00:00:00Z","timestamp":1490227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"North Carolina State University Firestone Canine Research Endowment"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine any loss of function of a single\u2010use bipolar vessel sealing device after repeated sterilization and use on canine carotid arteries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Ex vivo; randomized block design (dog).<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample population<\/jats:title><jats:p>Carotid artery segments (n\u2009=\u200990) from 15 canine cadavers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Six 10\u2010mm LigaSure Atlas 20 cm devices (Covidien Inc, Minneapolis, Minnesota) were used to seal canine carotid artery segments in one cadaver, then resterilized using ethylene oxide and reused in a second cadaver, and so on, for a total of 15 uses\/15 cadavers per LigaSure. Sealing times and bursting pressures of each carotid artery segment after each use were recorded. Charring and sticking at each seal location was qualitatively assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean (SD) sealing time for all segments was 5.3 (1.4) seconds, ranging from 2.7 to 9.5 seconds. There was no significant change in sealing time for successive uses (<jats:italic>P<\/jats:italic>\u2009=\u2009.117). The mean (SD) bursting pressure for all segments was 1041.3 (316.7) mm Hg, ranging from 355 to 1555 mm Hg. There was no change in bursting pressure across uses (<jats:italic>P<\/jats:italic>\u2009=\u2009.57). Moderate sticking and charring occurred at each time point but was not subjectively different throughout the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The LigaSure Atlas vessel sealing device can be used and resterilized with ethylene oxide up to 15 times with no change in sealing time or bursting pressure of the seal.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.12648","type":"journal-article","created":{"date-parts":[[2017,3,24]],"date-time":"2017-03-24T10:37:59Z","timestamp":1490351879000},"page":"501-506","source":"Crossref","is-referenced-by-count":20,"title":["Carotid artery bursting pressure and seal time after multiple uses of a vessel sealing device"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0899-1243","authenticated-orcid":false,"given":"Jocelin S.","family":"Blake","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine North Carolina State University Raleigh North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian J.","family":"Trumpatori","sequence":"additional","affiliation":[{"name":"Department of Surgery Veterinary Specialty Hospital of the Carolinas Cary North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle G.","family":"Mathews","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine North Carolina State University Raleigh North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily H.","family":"Griffith","sequence":"additional","affiliation":[{"name":"Department of Statistics, College of Agriculture and Life Sciences North Carolina State University Raleigh North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.5326\/JAAHA-MS-5981"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004640080025"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-002-8833-7"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-016-4778-0"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004649900733"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.74.6.934"},{"key":"e_1_2_7_8_1","unstructured":"Medical Device User Fee and Modernization Act of 2002 including changes made by the Medical Devices Technical Corrections Act USFDA; 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