{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:47:18Z","timestamp":1762102038053},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,4,29]],"date-time":"2017-04-29T00:00:00Z","timestamp":1493424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare long\u2010term outcome of<jats:italic>Salmonella<\/jats:italic>\u2010positive versus<jats:italic>Salmonella<\/jats:italic>\u2010negative horses discharged from hospital after colic surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Retrospective case\u2010control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Horses discharged from the hospital after colic surgery. For each horse with positive culture for<jats:italic>Salmonella enterica<\/jats:italic>(SAL\u2010POS, n\u2009=\u200959), at least 2 horses testing negative for<jats:italic>S. enterica<\/jats:italic>(SAL\u2010NEG, n\u2009=\u2009119) were enrolled.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Owners were interviewed via phone at least 12 months after surgery regarding: (1) complications after discharge from the hospital; (2) duration of survival; and (3) return to prior or intended use. Association between immediate postoperative clinical variables such as<jats:italic>Salmonella<\/jats:italic>status and long\u2010term measures of outcome was tested via ratios (odds ratio [OR]) and 95% confidence intervals. Data were analyzed for survival using a Cox proportional hazards model and for return to use using multivariable logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>SAL\u2010POS horses had a higher OR of surgical site infection (2.7 [1.1\u20106.9]<jats:italic>P<\/jats:italic>\u2009=\u2009.027) and weight loss (6.8 [1.8\u201026.1]<jats:italic>P<\/jats:italic>\u2009=\u2009.002). At the time of follow\u2010up, there were 53\/56 (95%) SAL\u2010POS and 99\/118 (84%) SAL\u2010NEG horses alive. The final multivariable model for nonsurvival included postoperative colic (hazard ratio 7.6 [2.8\u201019.2]<jats:italic>P<\/jats:italic>\u2009=\u2009.002) and the interaction between<jats:italic>Salmonella<\/jats:italic>status and duration of rectal temperature\u2009&gt;\u2009103\u00b0F postoperatively (SAL\u2010POS 1.04 [1.01\u20101.07] and SAL\u2010NEG 1.16 [1.06\u20101.25],<jats:italic>P<\/jats:italic>\u2009=\u2009.005). The majority of horses returned to their intended use regardless of their SAL\u2010POS (38\/50, 76%) or SAL\u2010NEG (77\/96, 80%,<jats:italic>P<\/jats:italic>\u2009=\u2009.498) status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:italic>Salmonella<\/jats:italic>\u2010positive horses that survive to discharge from the hospital after colic surgery have similar risks of long\u2010term complications (colic\/diarrhea), survival, and return to function than<jats:italic>Salmonella<\/jats:italic>\u2010negative horses.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.12660","type":"journal-article","created":{"date-parts":[[2017,5,2]],"date-time":"2017-05-02T01:42:34Z","timestamp":1493689354000},"page":"780-788","source":"Crossref","is-referenced-by-count":12,"title":["Influence of<i>Salmonella<\/i>status on the long\u2010term outcome of horses after colic surgery*"],"prefix":"10.1111","volume":"46","author":[{"given":"Louise L.","family":"Southwood","sequence":"first","affiliation":[{"name":"Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine University of Pennsylvania Kennett Square Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Lindborg","sequence":"additional","affiliation":[{"name":"Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine University of Pennsylvania Kennett Square Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Myers","sequence":"additional","affiliation":[{"name":"Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine University of Pennsylvania Kennett Square Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen W.","family":"Aceto","sequence":"additional","affiliation":[{"name":"Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine University of Pennsylvania 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