{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T10:53:32Z","timestamp":1793444012170,"version":"4.5.0"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,2,5]],"date-time":"2018-02-05T00:00:00Z","timestamp":1517788800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the complications and outcome after total prostatectomy in dogs with histologically confirmed prostatic carcinoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Multi\u2010institutional retrospective case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>25 client\u2010owned dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records of dogs undergoing total prostatectomy were reviewed from 2004 to 2016. Data retrieved included signalment, presenting signs, preoperative clinical findings, laboratory data, diagnostic imaging, surgical technique, histologic diagnosis, postoperative complications, occurrence of postoperative metastasis, and survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010five dogs underwent total prostatectomy for prostatic carcinoma. Urinary anastomotic techniques included urethrourethral anastomosis in 14 dogs, cystourethral anastomosis in 9 dogs, ureterocolonic anastomosis in 1 dog, and anastomosis between the bladder neck and penile urethra in 1 dog. All dogs survived to discharge. Fifteen dogs were diagnosed with transitional cell carcinoma, 8 dogs with prostatic adenocarcinoma, 1 with prostatic cystadenocarcinoma, and 1 with an undifferentiated carcinoma. Permanent postoperative urinary incontinence was present in 8 of 23 dogs. The median survival time was shorter in dogs with extracapsular tumor extension compared with those with intracapsular tumors. The overall median survival time was 231 days (range, 24\u20101255), with 1\u2010 and 2\u2010year survival rates equal to 32% and 12%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion and Clinical Significance<\/jats:title><jats:p>Total prostatectomy, combined with adjunct therapies, prolongs survival and lowers complication rates compared to previous reports of dogs with prostatic carcinoma. It should be noted, however, that case selection likely played a significant role in postoperative outcome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.12768","type":"journal-article","created":{"date-parts":[[2018,2,5]],"date-time":"2018-02-05T10:46:46Z","timestamp":1517827606000},"page":"367-377","source":"Crossref","is-referenced-by-count":55,"title":["Total prostatectomy as a treatment for prostatic carcinoma in 25 dogs"],"prefix":"10.1111","volume":"47","author":[{"given":"Tristram C.","family":"Bennett","sequence":"first","affiliation":[{"name":"Brisbane Veterinary Specialist Centre Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad M.","family":"Matz","sequence":"additional","affiliation":[{"name":"Auburn University College of Veterinary Medicine Auburn Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph A.","family":"Henderson","sequence":"additional","affiliation":[{"name":"Auburn University College of Veterinary Medicine Auburn Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney C.","family":"Straw","sequence":"additional","affiliation":[{"name":"Australian Animal Cancer Foundation Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julius M.","family":"Liptak","sequence":"additional","affiliation":[{"name":"Alta Vista Animal Hospital Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura E.","family":"Selmic","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine University of Illinois Urbana\u2010Champaign Urbana Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Collivignarelli","sequence":"additional","affiliation":[{"name":"Clinica Veterinaria Malpensa Samarate Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Buracco","sequence":"additional","affiliation":[{"name":"University of Turin Grugliasco Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,2,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.20590"},{"key":"e_1_2_7_3_1","first-page":"1623","article-title":"Clinical and pathologic features of prostatic adenocarcinoma in sexually intact and castrated dogs: 31 dogs (1970\u20101987)","volume":"199","author":"Bell FW","year":"1991","journal-title":"J Am Anim Hosp Assoc."},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.2460\/javma.1992.200.08.1119","article-title":"Study of prostatic disease in dogs: 177 cases (1981\u20101986)","volume":"200","author":"Krawiec DR","year":"1992","journal-title":"J Am Vet Med Assoc."},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-7207(02)00261-7"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.41-2-131"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2008.07.012"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0045(20001001)45:2<173::AID-PROS12>3.0.CO;2-R"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5810.2004.00035.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950x.2004.04067.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"48","DOI":"10.2460\/javma.1987.190.01.48","article-title":"Intraoperative radiotherapy of carcinoma of the prostate gland in ten dogs","volume":"190","author":"Turrel JM.","year":"1987","journal-title":"J Am Vet Med Assoc."},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1989.tb01035.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.229.2.226"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.242.1.59"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2003.tb02440.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.tvjl.2007.08.001","article-title":"Preliminary results of intraoperative photodynamic therapy with 5\u2010aminolevulinic acid in dogs with prostate carcinoma","volume":"178","author":"L'Epplattenier HF","year":"2008","journal-title":"Vet J."},{"key":"e_1_2_7_17_1","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.2460\/javma.230.8.1184","article-title":"Outcome of and complications associated with tube cystostomy in dogs and cats: 76 cases (1995\u20102006)","volume":"203","author":"Beck AL","year":"2007","journal-title":"J Am Vet Med Assoc."},{"key":"e_1_2_7_18_1","doi-asserted-by":"crossref","first-page":"496","DOI":"10.2460\/javma.1995.206.04.496","article-title":"Placement of a permanent cystostomy catheter to relieve urine outflow obstruction in dog with transitional cell carcinoma","volume":"206","author":"Smith JD","year":"1995","journal-title":"J Am Vet Med Assoc."},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1994.tb03232.x"},{"key":"e_1_2_7_20_1","first-page":"906","article-title":"Clinical evaluation of mitoxantrone and piroxicam in a canine model of human invasive urinary bladder carcinoma","volume":"9","author":"Henry CJ","year":"2003","journal-title":"Clin Cancer Res."},{"key":"e_1_2_7_21_1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1476-5810.2005.00070.x","article-title":"Carboplatin and piroxicam therapy in 31 dogs with transitional cell carcinoma of the urinary bladder","volume":"2","author":"Boria PA","year":"2005","journal-title":"Vet Comp Oncol."},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12533"},{"key":"e_1_2_7_23_1","first-page":"512","article-title":"Subtotal intracapsular prostatectomy as a useful treatment for advanced\u2010stage prostatic malignancies","volume":"47","author":"Vlasin M","year":"2006","journal-title":"J Vet Intern Med."},{"key":"e_1_2_7_24_1","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1111\/j.1532-950X.2006.00165.x","article-title":"Partial prostatectomy using Nd:YAG laser for management of canine prostate carcinoma","volume":"35","author":"L'Epplattenier HF","year":"2006","journal-title":"Vet Surg."},{"key":"e_1_2_7_25_1","first-page":"557","volume-title":"Withrow and MacEwen's Small Animal Clinical Oncology","author":"Lawrence JA","year":"2014"},{"key":"e_1_2_7_26_1","first-page":"385","article-title":"Urodynamic alterations associated with clinical prostatic diseases and prostatic surgery in 23 dogs","volume":"25","author":"Basinger RR","year":"1989","journal-title":"J Am Anim Hosp Assoc."},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1053\/svms.2000.7304"},{"key":"e_1_2_7_28_1","first-page":"50","article-title":"Complications of prostatic surgery","volume":"20","author":"Hardie EM","year":"1984","journal-title":"J Am Anim Hosp Assoc."},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1991.tb01255.x"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2007.tb02927.x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4320(00)00101-9"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1987.tb00978.x"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-32-3-211"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2012.00946.x"}],"container-title":["Veterinary Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvsu.12768","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vsu.12768","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T17:48:06Z","timestamp":1751305686000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vsu.12768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,5]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["10.1111\/vsu.12768"],"URL":"https:\/\/doi.org\/10.1111\/vsu.12768","archive":["Portico"],"relation":{},"ISSN":["0161-3499","1532-950X"],"issn-type":[{"value":"0161-3499","type":"print"},{"value":"1532-950X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,5]]}}}