{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T15:35:55Z","timestamp":1784302555101,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T00:00:00Z","timestamp":1526515200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the ability of vaporized hydrogen peroxide (VHP) to sterilize a single\u2010use single\u2010incision laparoscopic surgery port and its associated components after repeated simulated uses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Prospective in vitro experimental study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample population<\/jats:title><jats:p>Six single\u2010use single\u2010incision laparoscopic surgery ports with associated cannulas and insufflation tubing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ports, cannulas, and tubing were subjected to 10 cycles of simulated use, bacterial inoculation with <jats:italic>Staphylococcus pseudintermedius<\/jats:italic> and <jats:italic>Escherichia coli<\/jats:italic>, decontamination and sterilization, and testing via culture based on their treatment group designation. Bacteriological scores were compared among the negative control, positive control, and 4 treated ports and components.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no difference in bacteriological scores between treated ports, cannulas, and insufflation tubing and the negative control port and components. Bacteriological scores of ports and components undergoing 6\u201010 cycles were not significantly different from scores of ports and components undergoing 5 or fewer sterilization cycles. No difference was found in detection of bacteria from treated ports by biopsy of the foam versus sampling via wash.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study suggests that a single\u2010use single\u2010incision laparoscopic port and its associated components can be effectively sterilized after multiple simulated uses by using VHP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>Reuse of a single\u2010use single\u2010incision laparoscopic port is a safe and effective method of cost reduction in veterinary patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.12905","type":"journal-article","created":{"date-parts":[[2018,5,18]],"date-time":"2018-05-18T05:34:45Z","timestamp":1526621685000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Efficacy of vaporized hydrogen peroxide for repeated sterilization of a single\u2010use single\u2010incision laparoscopic surgery port"],"prefix":"10.1111","volume":"48","author":[{"given":"Valery F.","family":"Scharf","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine North Carolina State University  Raleigh North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Dent","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine North Carolina State University  Raleigh North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan E.","family":"Jacob","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine North Carolina State University  Raleigh North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon","family":"Moore","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine North Carolina State University  Raleigh North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.227.921"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.243.5.703"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2009.00572.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2004.04003.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2011.00835.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/147323001204000234"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12344"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.249.3.299"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2014.12284.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-013-3411-8"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2013.12073.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(97)70233-5"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-011-1884-7"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-001-9190-7"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2010.04.003"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2010.08.003"},{"key":"e_1_2_7_18_1","unstructured":"MichaudGY.Guidance for Industry and FDA Staff\u2014Medical Device User Fee and Modernization Act of 2002 Validation Data in Premarket Notification Submissions (510(k)s) for Reprocessed Single\u2010Use Medical Devices.https:\/\/www.fda.gov\/downloads\/MedicalDevices\/DeviceRegulationandGuidance\/GuidanceDocuments\/ucm071441.pdf. 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