{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T15:10:48Z","timestamp":1788793848569,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,1,21]],"date-time":"2019-01-21T00:00:00Z","timestamp":1548028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Kennel Club Charitable Trust has provided support for the BOAS research group at Cambridge and funded whole-body barometric plethysmography"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine whether the sensitivity of clinical examination for assessing upper airway disease severity in 3 breeds of brachycephalic dogs can be improved by incorporating an exercise test (ET) or by auscultation of a laryngeal stridor to predict laryngeal collapse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Prospective clinical study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Client\u2010owned brachycephalic dogs (n\u2009=\u200944 ET; n\u2009=\u200957 laryngeal stridor assessment).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In the first part of the study, clinical examinations were performed at rest and after 5\u2010minute walk and 3\u2010minute trot tests, and a grade reflective of brachycephalic obstructive airway syndrome (BOAS) severity was assigned. Whole\u2010body barometric plethysmography was used as a comparative, objective measure of disease severity. In the second part of the study, the degree of laryngeal collapse present in dogs undergoing BOAS surgery was compared to pre\u2010exercise and postexercise laryngeal stridor detected during functional testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The sensitivity of clinical examination for BOAS diagnosis was 56.7% pre\u2010ET, 70% after a 5\u2010minute walk test, and 93.3% after a 3\u2010minute trot test. The sensitivity of laryngeal stridor as a predictor of laryngeal collapse was improved after exercise (70%) compared with before exercise (60%). Specificity of laryngeal stridor for laryngeal collapse was 100% (pre\u2010exercise and postexercise).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The sensitivity of clinical examination for BOAS diagnosis was improved by inclusion of an ET, particularly the 3\u2010minute trot test. Audible laryngeal stridor was highly specific but only moderately sensitive for laryngeal collapse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>Inclusion of a 3\u2010minute trot test and careful auscultation for laryngeal stridor are recommended during BOAS assessment of brachycephalic dogs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13159","type":"journal-article","created":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T09:34:16Z","timestamp":1548149656000},"page":"488-496","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Validation of exercise testing and laryngeal auscultation for grading brachycephalic obstructive airway syndrome in pugs, French bulldogs, and English bulldogs by using whole\u2010body barometric plethysmography"],"prefix":"10.1111","volume":"48","author":[{"given":"Julia","family":"Riggs","sequence":"first","affiliation":[{"name":"The Queen's Veterinary School Hospital University of Cambridge Cambridge United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nai\u2010Chieh","family":"Liu","sequence":"additional","affiliation":[{"name":"The Queen's Veterinary School Hospital University of Cambridge Cambridge United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn R.","family":"Sutton","sequence":"additional","affiliation":[{"name":"The Queen's Veterinary School Hospital University of Cambridge Cambridge United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Sargan","sequence":"additional","affiliation":[{"name":"The Queen's Veterinary School Hospital University of Cambridge Cambridge United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane F.","family":"Ladlow","sequence":"additional","affiliation":[{"name":"The Queen's Veterinary School Hospital University of Cambridge Cambridge United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,1,21]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"10 Yearly Breed Statistics. 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