{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:17:33Z","timestamp":1773029853599,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T00:00:00Z","timestamp":1552953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the ability of a pre\u2010tied ligature loop (PLL) to create a seal against physiological airway pressures after total lung lobectomy and report outcomes in dogs requiring lung lobectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Ex vivo experimental randomized study and clinical case study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample population<\/jats:title><jats:p>Thirty cadaveric canine lung lobes and 5 client\u2010owned dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty canine lung lobes from dogs weighing 22.5\u201335\u2009kg were randomized to lobectomy with stapler, PLL, or suture ligation. After lobectomy, each bronchial stump was submerged in water, and the mainstem airway pressure was increased to 80\u2009mm Hg. Leakage was compared between techniques. The PLL was subsequently used in 5 dogs (17\u201325\u2009kg) with neoplastic disease requiring total lung lobectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two stapled and 4 sutured bronchial stumps leaked at supraphysiological pressures &gt;15\u2009mm Hg. One stapled bronchial stump failed at a physiological airway pressure (5\u2009mm Hg). None of the PLL lobectomies leaked. The incidence of bronchial stump failures did not differ among techniques (<jats:italic>P<\/jats:italic>\u2009=\u2009.15). Lung lobectomy was performed successfully with the PLL in 5 clinical cases with no intraoperative or postoperative complications; median follow\u2010up time was 6\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Bronchial ligation with the PLL reliably resisted physiological airway pressures and performed comparably to current standard techniques in cadavers. The PLL provided an adequate air and vascular seal in 5 clinical cases undergoing total lung lobectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical relevance<\/jats:title><jats:p>Pre\u2010tied ligature loops provide an alternative method for total lung lobectomy in dogs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13194","type":"journal-article","created":{"date-parts":[[2019,3,20]],"date-time":"2019-03-20T01:23:06Z","timestamp":1553044986000},"page":"570-577","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Evaluation of a pre\u2010tied ligature loop for canine total lung lobectomy"],"prefix":"10.1111","volume":"48","author":[{"given":"Anna M.","family":"Cronin","sequence":"first","affiliation":[{"name":"Department of Veterinary Medicine University of Cambridge Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sasja 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