{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:52:57Z","timestamp":1760921577526,"version":"3.40.5"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,6,5]],"date-time":"2019-06-05T00:00:00Z","timestamp":1559692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To report the use and long\u2010term outcome of dogs with surgical site infection (SSI) after tibial plateau leveling osteotomy (TPO), treated with an amikacin\u2010infused collagen sponge and implant removal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Retrospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Thirty\u2010one client\u2010owned dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records were reviewed for dogs with SSI after a TPLO that were treated with surgical implant removal and concurrent implantation of an amikacin\u2010infused collagen sponge. Relevant clinical and surgical data were recorded. The TPLO implants were routinely removed; the surgical site was swabbed for culture. The sponge was aseptically infused with amikacin prior to implantation. Postprocedure examinations consisted of visual inspection of the incision by the surgeon and lameness scoring.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010one dogs met all inclusion criteria. Median follow\u2010up time was 687\u2009days. Short\u2010term examination after implant removal and sponge implantation revealed uneventful incisional healing in 24 dogs. Six (19.4%) dogs exhibited inflamed incision sites a median of 4\u2009days (range, 3\u20139) postoperatively that resolved without additional treatment. One (3.2%) dog required empirical antibiotic treatment 7\u2009days postoperatively but was lost to long\u2010term follow\u2010up. Long\u2010term follow\u2010up examination revealed no clinical evidence of SSI recurrence and no lameness in the remaining 30 cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Surgical implant removal and implantation of an absorbable collagen sponge infused with amikacin alone was an effective treatment for postoperative TPLO SSI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>This procedure had a 96.8% long\u2010term resolution of SSI. It should be considered as a treatment option for TPLO SSI.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13249","type":"journal-article","created":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T05:53:20Z","timestamp":1559800400000},"page":"700-706","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Use of an amikacin\u2010infused collagen sponge concurrent with implant removal for treatment of tibial plateau leveling osteotomy surgical site infection in 31 cases"],"prefix":"10.1111","volume":"48","author":[{"given":"Sylvia J.","family":"Lee","sequence":"first","affiliation":[{"name":"Surgery Department BluePearl Veterinary Partners  Tampa Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4606-3632","authenticated-orcid":false,"given":"Steven W.","family":"Frederick","sequence":"additional","affiliation":[{"name":"Surgery Department BluePearl Veterinary Partners  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