{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T22:53:17Z","timestamp":1783119197481,"version":"3.54.6"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T00:00:00Z","timestamp":1560988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To report the surgical treatment and outcome of a non\u2010ambulatory calf with cervical vertebral ostoeomyelitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Clinical report.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample population<\/jats:title><jats:p>One 3.5\u2010month\u2010old female mixed\u2010breed calf with tetraparesis of 3\u2009months duration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>After computed tomography\u2010guided bone biopsy, a bacterial osteolytic lesion within the body of the fourth cervical vertebrae (C4) and resultant pathologic compression fracture clinically resulting in full tetraparesis was diagnosed in the calf. Culture results from the lesion within C4 confirmed a diagnosis of <jats:italic>Trueperella pyogenes<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Poor response to medical management justified surgical debridment of the lesion in C4 and subsequent stabilization of the cervical vertebral column. A three\u2010part procedure was performed including (1) debridement of the C4, (2) bilateral ventral vertebral stabilization from C3 to C5, and (3) placement of ampicillin\u2010impregnated plaster of Paris beads within the body of C4. With postoperative physical rehabilitation, the calf regained full ambulatory function. At 1\u2010month follow\u2010up, the calf remained ambulatory with mild proprioceptive ataxia and no evidence of implant failure. At annual recheck, the calf had gained 208\u2009kg and remained fully ambulatory with no residual neurologic deficits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Surgical intervention and use of antibiotic\u2010impregnated implants offered a viable alternative to long\u2010term medical management of vertebral osteomyelitis in the calf reported here.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>This case identifies surgical intervention as a potential means for improving outcomes in a historically fatal condition of production animals.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13251","type":"journal-article","created":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T10:24:13Z","timestamp":1561026253000},"page":"1064-1070","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Surgical intervention for vertebral osteomyelitis in a calf"],"prefix":"10.1111","volume":"48","author":[{"given":"Sara K.","family":"Shivapour","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences Royal Veterinary College  North Mymms United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole D.","family":"Jackson","sequence":"additional","affiliation":[{"name":"eIMAGING  Fort Worth Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"Schleining","sequence":"additional","affiliation":[{"name":"Department of Large Animal Clinical Sciences Texas A&amp;M University  College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda J.","family":"Kreuder","sequence":"additional","affiliation":[{"name":"Department of Veterinary Diagnostic and Production Animal Medicine Iowa State University  Ames Iowa"},{"name":"Department of Veterinary Microbiology and Preventative Medicine Iowa State University  Ames Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina G.","family":"Miles","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences Iowa State University  Ames Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas D.","family":"Jeffery","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences Texas A&amp;M University  College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,20]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.152.25.782"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.164.23.723"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1090-0233(97)80027-5"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-6148-7-53"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.152.20.630"},{"key":"e_1_2_5_7_1","first-page":"700","article-title":"Cervical diskospondylitis in a calf: clinical, radiographic, and necropsy findings","volume":"45","author":"Della Libera A","year":"2004","journal-title":"Can Vet J."},{"issue":"4","key":"e_1_2_5_8_1","first-page":"114","article-title":"A survey of vertebral abscesses in domestic animals in Ontario","volume":"16","author":"Finley GG","year":"1975","journal-title":"Can Vet J."},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2008.00454.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.160.5.162"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.158.17.600"},{"key":"e_1_2_5_12_1","unstructured":"VetONE.Vitamin E\u2010AD (injectable suspension) [package insert].Boise ID:MWI Animal Health;2016."},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7234-3209-8.50011-X"},{"key":"e_1_2_5_14_1","unstructured":"SOP (String of Pearls).User guide.Huddersfield West Yorkshire United Kingdom:Orthomed;2016."},{"key":"e_1_2_5_15_1","unstructured":"Screws drill bits taps and guide wires.Reference Chart.West Chester PA:Synthes;2002."},{"key":"e_1_2_5_16_1","unstructured":"Polyflex (ampicillin for injectable suspension) [package insert]. 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