{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T21:00:13Z","timestamp":1788987613447,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,11,14]],"date-time":"2019-11-14T00:00:00Z","timestamp":1573689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000836","name":"University of Liverpool","doi-asserted-by":"publisher","award":["Barry Edwards Memorial Fund"],"award-info":[{"award-number":["Barry Edwards Memorial Fund"]}],"id":[{"id":"10.13039\/501100000836","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate two different barbed sutures for closure of pelvic flexure enterotomies and compare results achieved with two previously described closure techniques.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Ex vivo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample population<\/jats:title><jats:p>Twenty\u2010four fresh cadaver adult equine large colons.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cadavers were randomly assigned to four closure groups (n = 6 each group): single\u2010layer absorbable suture, double\u2010layer absorbable suture, single\u2010layer unidirectional barbed suture, or single\u2010layer bidirectional barbed suture. Construction time, luminal reduction (percentage), bursting pressure, and method of failure were measured. Cost, leakage, exposed suture, and general appearance were recorded. Comparisons were performed with one\u2010way analysis of variance and post hoc Bonferroni test (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Double\u2010layer absorbable closure had the highest bursting pressure (mean = 178.5\u2009mm Hg, SD = 9.79, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) but took more time (<jats:italic>P<\/jats:italic> = .001) compared with all other groups. The construction time of both barbed suture closures did not differ from the single\u2010layer closure (<jats:italic>P<\/jats:italic>\u2009&gt;\u2009.06). Bursting strengths of both unidirectional (mean = 91.6\u2009mm Hg, SD = 5.57) and bidirectional (mean = 87.5\u2009mm Hg, SD = 8.69) barbed sutures were lower (<jats:italic>P<\/jats:italic>\u2009&gt;\u2009.006 for both) than those of both single\u2010 (mean = 117.6\u2009mm Hg, SD = 11.69) and double\u2010layer (mean = 178.5\u2009mm Hg, SD = 9.79) closures. Unidirectional barbed suture closure had a reduction in lumen diameter (<jats:italic>P<\/jats:italic> = .004) compared with bidirectional and single\u2010layer closures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Enterotomy closures with the two different barbed suture patterns were comparable in bursting strength and construction time. However, the barbed suture patterns had lower bursting strength compared with traditional single\u2010 and double\u2010layer closures. Unidirectional barbed suture closure also reduced lumen diameter.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>Closure of a large colon enterotomy with barbed suture patterns may be less secure than single\u2010 and double\u2010layer suture closure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13353","type":"journal-article","created":{"date-parts":[[2019,11,14]],"date-time":"2019-11-14T13:19:44Z","timestamp":1573737584000},"page":"487-495","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Ex vivo comparison of barbed sutures for pelvic flexure enterotomy in horses"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1925-5698","authenticated-orcid":false,"given":"Matthew","family":"Sinovich","sequence":"first","affiliation":[{"name":"The Philip Leverhulme Equine Hospital, University of Liverpool  Neston United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debbie C.","family":"Archer","sequence":"additional","affiliation":[{"name":"The Philip Leverhulme Equine Hospital, University of Liverpool  Neston United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natascha V.","family":"Meunier","sequence":"additional","affiliation":[{"name":"The Epidemiology, Economics and Risk Assessment Group, The Roslin Institute, Royal (Dick) School of Veterinary Studies, Easter Bush  United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padraig G.","family":"Kelly","sequence":"additional","affiliation":[{"name":"The Philip Leverhulme Equine Hospital, University of Liverpool  Neston United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-48420-6.00037-5"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12633"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/279730"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0739(17)30240-7"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/ctep.2002.35577"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2013.12065.x"},{"issue":"6","key":"e_1_2_6_8_1","first-page":"665","article-title":"Comparison of single layer staple closure versus double layer hand\u2010sewn closure for equine pelvic flexure enterotomy","volume":"53","author":"Rosser JM","year":"2012","journal-title":"Can Vet J."},{"key":"e_1_2_6_9_1","unstructured":"Medtronic (UK). Wound closure.https:\/\/www.medtronic.com\/covidien\/en-gb\/products\/wound-closure.html. Accessed November 4 2019."},{"key":"e_1_2_6_10_1","unstructured":"Surgical Specialties Corporation. Quill barbed sutures.https:\/\/www.surgicalspecialties.com\/suture-wound-closure-brands\/quill-barbed-sutures\/. Accessed November 4 2019."},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2013.12081.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2014.01.041"},{"issue":"3","key":"e_1_2_6_13_1","first-page":"107","article-title":"Barbed suture: a review of the technology and clinical uses in obstetrics and gynecology","volume":"6","author":"Greenberg JA","year":"2013","journal-title":"Rev Obstet Gynecol."},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1553350614554235"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12719"},{"key":"e_1_2_6_16_1","unstructured":"BarceloF MarcatiliM PollockP. Comparison of incisional bursting strength of a bidirectional absorbable knotless suture material versus a standard continuous absorbable suture material for closure of the equine linea alba. 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