{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:30:53Z","timestamp":1790742653530,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,1,20]],"date-time":"2020-01-20T00:00:00Z","timestamp":1579478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Arthrex Inc"},{"name":"Tata Endowment"},{"name":"Veterinary Orthopedic Society Hohn Johnson Grant"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the 12\u2010month survival of intra\u2010articular, decellularized allografts for the treatment of cranial cruciate ligament disease (CCLD) in dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Prospective case series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Twenty client\u2010owned dogs with spontaneous CCL rupture.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Affected stifles were treated solely by implantation of an intra\u2010articular, decellularized, deep digital flexor tendon allograft. Functional outcome was evaluated at baseline and at 6 and 12\u2009months after surgery with the Liverpool Osteoarthritis for Dogs questionnaire and force platform gait analysis. At 12\u2009months after surgery, dogs underwent arthroscopy to visually assess the allografts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Scores on owner questionnaires (improved 62.5%;\n                      <jats:italic>P<\/jats:italic>\n                      = .005) and ground reaction forces (improved 34.4%;\n                      <jats:italic>P<\/jats:italic>\n                      = .017) were improved in all dogs 12\u2009months after surgery. Dogs with an intact graft (IG) were more likely to have a successful outcome compared with dogs with a torn graft (\n                      <jats:italic>P<\/jats:italic>\n                      = .011). According to arthroscopy, 45% of grafts seemed to survive at 12\u2009months after surgery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>About half of intra\u2010articular allografts survived 12\u2009months after implantation in CCL\u2010deficient stifles. Dogs with IG had successful outcomes at 12\u2009months after surgery according to assessment by force platform gait analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical significance<\/jats:title>\n                    <jats:p>These results preclude immediate clinical application but provide evidence to justify further investigation of intra\u2010articular grafts as a repair option for CLLD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vsu.13379","type":"journal-article","created":{"date-parts":[[2020,1,20]],"date-time":"2020-01-20T07:11:16Z","timestamp":1579504276000},"page":"764-771","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Long\u2010term arthroscopic assessment of intra\u2010articular allografts for treatment of spontaneous cranial cruciate ligament rupture in the dog"],"prefix":"10.1111","volume":"49","author":[{"given":"Jeffery J.","family":"Biskup","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences College of Veterinary Medicine, Oregon State University, Corvallis Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Conzemius","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences and Clinical Investigation Center University of Minnesota St Paul Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12445"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-014-0266-8"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.243.5.675"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2005.00021.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2009.00628.x"},{"key":"e_1_2_7_7_1","first-page":"1095","article-title":"Comparison of radiographic osteoarthritis scores in dogs less than 24 months or greater than 24 months following tibial plateau leveling osteotomy","volume":"53","author":"DeLuke AM","year":"2012","journal-title":"Can Vet 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