{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:08:07Z","timestamp":1747188487791,"version":"3.40.5"},"reference-count":34,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T00:00:00Z","timestamp":1581552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Ontario Veterinary College Pet Trust Fund (to A.S)."}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the performance of an endoscopic 3\u2010mm electrothermal bipolar vessel sealing device (EBVS) intended for single use after multiple use\u2010and\u2010resterilization cycles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Ex vivo study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample population<\/jats:title><jats:p>Eight 3\u2010mm EBVS handpieces.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Handpieces were subjected to a maximum of 15\u2009cycles of testing, including simulated surgery, sealing and burst pressure testing of porcine carotid arteries, reprocessing, and hydrogen peroxide plasma resterilization. Failure was defined as two sequential vascular seal leakage events occurring at &lt;250\u2009mm Hg. Histological evaluation, maximum external temperature of the jaws, sealing time, tissue adherence, jaw surface characterization, and mechanical deterioration were studied. Failure rate was analyzed by using a Kaplan\u2013Meier curve. Linear and ordinal logistic mixed models were used to analyze sealing time, handpiece jaw temperature, and adherence score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean\u2009\u00b1\u2009SD diameter of arteries was 3.22\u2009\u00b1\u20090.35\u2009mm. Failure was observed starting at cycle 10 and going up to cycle 13 in 37.5% (3\/8) of the handpieces. Tissue adherence increased after each cycle (<jats:italic>P<\/jats:italic> &lt;\u2009.001). Maximum external temperature (79.8\u00b0C\u2009\u00b1\u200913.9\u00b0C) and sealing time (1.8\u2009\u00b1\u20090.5\u2009seconds) were not significantly different throughout cycles up to failure. A flatter surface and large scratches were observed microscopically throughout the jaw surface after repeated use and resterilization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The 3\u2010mm EBVS handpiece evaluated in this study can be considered safe to use for up to nine reuse\u2010and\u2010resterilization cycles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>These data provide the basis for establishing preliminary guidelines for the reuse and hydrogen peroxide plasma resterilization of an endoscopic 3\u2010mm EBVS handpiece.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13396","type":"journal-article","created":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T13:35:28Z","timestamp":1581600928000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of the performance of an endoscopic 3\u2010mm electrothermal bipolar vessel sealing device intended for single use after multiple use\u2010and\u2010resterilization cycles"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2274-6183","authenticated-orcid":false,"given":"Juliany Gomes","family":"Quitzan","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine and Animal Science, Sao Paulo State University  Botucatu Sao Paulo Brazil"},{"name":"Department of Clinical Studies Ontario Veterinary College, University of Guelph  Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8095-9339","authenticated-orcid":false,"given":"Ameet","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Clinical Studies Ontario Veterinary College, University of Guelph  Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3612-5548","authenticated-orcid":false,"given":"Hugues","family":"Beaufrere","sequence":"additional","affiliation":[{"name":"Department of Clinical Studies Ontario Veterinary College, University of Guelph  Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Valverde","sequence":"additional","affiliation":[{"name":"Department of Clinical Studies Ontario Veterinary College, University of Guelph  Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon","family":"Lillie","sequence":"additional","affiliation":[{"name":"Department of Pathobiology Ontario Veterinary College, University of Guelph  Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masoomeh","family":"Salahshoor","sequence":"additional","affiliation":[{"name":"School of Engineering, College of Engineering and Physical Sciences, University of Guelph  Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Bardelcik","sequence":"additional","affiliation":[{"name":"School of Engineering, College of Engineering and Physical Sciences, University of Guelph  Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2502-2380","authenticated-orcid":false,"given":"Tarek M.","family":"Saleh","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences Ontario Veterinary College, University of Guelph  Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,2,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-016-4778-0"},{"key":"e_1_2_7_3_1","first-page":"193","article-title":"Consistency and sealing of advanced bipolar tissue sealers","volume":"8","author":"Chekan EG","year":"2015","journal-title":"Med Devices (Auckl)."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-012-2177-8"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.104016"},{"key":"e_1_2_7_6_1","unstructured":"Bolder Surgical. 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