{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T15:17:21Z","timestamp":1789831041570,"version":"4.0.1"},"reference-count":56,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,4,11]],"date-time":"2020-04-11T00:00:00Z","timestamp":1586563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To report recovery of ambulation of dogs treated with extended thoracolumbar durotomy for severe spinal cord injury caused by intervertebral disc herniation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Descriptive cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Twenty\u2010six consecutive paraplegic dogs presented with loss of deep pain sensation after acute thoracolumbar intervertebral disc herniation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Each dog underwent routine diagnostic assessment and surgery for removal of extradural herniated intervertebral disc, followed by a four\u2010vertebral body length durotomy centered on the herniated disc. Each dog was followed up until it was able to walk 10 steps without assistance or until 6\u2009months after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixteen of 26 dogs recovered to walk unaided (all but one also recovered fecal and urinary continence), and six dogs did not; four dogs were lost to follow\u2010up. One dog was euthanized because of signs consistent with progressive myelomalacia. There was no evidence of detrimental effects of durotomy within the period of study. Using Bayesian analysis, we found a point estimate of successful outcome of 71% with 95% credible interval from 52% to 87%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Extended durotomy seemed to improve the outcome of dogs in our case series without increase in morbidity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>Extended durotomy appears safe and may improve the outcome of dogs with severe thoracolumbar mixed contusion and compressive injuries associated with acute intervertebral disc extrusion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13423","type":"journal-article","created":{"date-parts":[[2020,4,11]],"date-time":"2020-04-11T15:20:20Z","timestamp":1586618420000},"page":"884-893","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Extended durotomy to treat severe spinal cord injury after acute thoracolumbar disc herniation in dogs"],"prefix":"10.1111","volume":"49","author":[{"given":"Nick D.","family":"Jeffery","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences Texas A&amp;M University  College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe M.","family":"Mankin","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences Texas A&amp;M University  College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Ito","sequence":"additional","affiliation":[{"name":"Division of Veterinary Neurology School of Veterinary Medicine, Nihon University  Fujisawa Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Elizabeth","family":"Boudreau","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences Texas A&amp;M University  College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1981-0276","authenticated-orcid":false,"given":"Sharon C.","family":"Kerwin","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences Texas A&amp;M University  College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon M.","family":"Levine","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences Texas A&amp;M University  College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya S.","family":"Krasnow","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences Texas A&amp;M University  College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa N.","family":"Andruzzi","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences Texas A&amp;M University  College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cody J.","family":"Alcott","sequence":"additional","affiliation":[{"name":"Veterinary Specialty Center of Tucson  Tucson Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Granger","sequence":"additional","affiliation":[{"name":"CVS Referrals, Bristol Veterinary Specialists at Highcroft  Bristol United Kingdom"},{"name":"The Royal Veterinary College, University of London  Hatfield Hertfordshire United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1970.tb05595.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7216-6706-5.00009-3"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2009.02.016"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1997.tb03303.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2016.12.008"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2010.06.001"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12653"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1972.tb06870.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2003.222.762"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.248.4.386"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.241.12.1617"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.13657"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2014.12102.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.14829"},{"key":"e_1_2_6_16_1","first-page":"225","article-title":"Spinal cord edema and changes in tissue content of Na+, K+, and Mg2+ after impact trauma in rats","volume":"52","author":"Demediuk P","year":"1990","journal-title":"Adv Neurol."},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2014.3543"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(76)90065-4"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1991.75.1.0015"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2009.00529.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2018.12.021"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1911.04260090100008"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(00)50004-7"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5288(18)33725-1"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5288(18)33985-7"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1632953"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2011.00909.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2016.4490"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000028"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2014.3668"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2016-314600"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2018.5775"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-016-1490-3"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2014.12319.x"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1080\/10790268.2019.1660840"},{"key":"e_1_2_6_36_1","first-page":"24","article-title":"Hemilaminectomy in dogs without deep pain perception","volume":"45","author":"Anderson SM","year":"1991","journal-title":"A retrospective study of 32 cases"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12463"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.14677"},{"key":"e_1_2_6_39_1","first-page":"619","article-title":"Lateral fenestration of thoracolumbar discs","volume":"11","author":"Flo GL","year":"1975","journal-title":"J Am Anim Hosp Assoc."},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.14651"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2011.00921.x"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1996.tb01371.x"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2005.tb02766.x"},{"key":"e_1_2_6_44_1","first-page":"254","article-title":"Molecular basis of vascular events following spinal cord injury","volume":"3","author":"Sinescu C","year":"2010","journal-title":"J Med Life."},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12653"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1632970"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2018.5961"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2009.1149"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.227.1454"},{"key":"e_1_2_6_50_1","first-page":"62","article-title":"Bilateral hemilaminectomy: a technique for extensive spinal decompression","author":"Swaim SF","year":"1976","journal-title":"Auburn Vet."},{"key":"e_1_2_6_51_1","first-page":"405","article-title":"Modifications in dorsolateral hemilaminectomy and disc fenestration in the dog","volume":"11","author":"Gage ED","year":"1975","journal-title":"J Am Anim Hosp Assoc."},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2003.64.1139"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2004.224.1808"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.14714"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.104579"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.15470"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.15439"}],"container-title":["Veterinary Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvsu.13423","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vsu.13423","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vsu.13423","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vsu.13423","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T10:02:03Z","timestamp":1693994523000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vsu.13423"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,11]]},"references-count":56,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1111\/vsu.13423"],"URL":"https:\/\/doi.org\/10.1111\/vsu.13423","archive":["Portico"],"relation":{},"ISSN":["0161-3499","1532-950X"],"issn-type":[{"value":"0161-3499","type":"print"},{"value":"1532-950X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,11]]},"assertion":[{"value":"2019-06-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}