{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:58:46Z","timestamp":1792180726477,"version":"4.4.0"},"reference-count":50,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the body composition of dogs with or without cranial cruciate ligament (CCL) disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Cross\u2010sectional.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Adult dogs in which CCL disease was diagnosed (n = 30) and adult dogs without clinical signs of orthopedic disease (n = 30).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Body weight, body condition score, and muscle condition score (MCS) were recorded. Body composition of the whole body and pelvic limbs were assessed by dual\u2010energy x\u2010ray absorptiometry. Body condition score, whole body, and pelvic limb body composition measurements were compared by using general linear mixed\u2010model analysis of variance. Muscle condition score between groups was assessed by using a Mann\u2013Whitney\n                      <jats:italic>U<\/jats:italic>\n                      test, while paired data were analyzed by using a Wilcoxon signed\u2010rank test.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Body fat percentage (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.0001) was higher in affected dogs (38.78% \u00b1 1.40) than in control dogs (27.49%\u2009\u00b1\u20091.24). Affected dogs had lower MCS (1.90\u2009\u00b1\u20090.13,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.0001) compared with control dogs (2.77\u2009\u00b1\u20090.08). The affected pelvic limb of affected dogs contained less lean soft tissues (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.0001) but more fat (\n                      <jats:italic>P<\/jats:italic>\n                      = .0451) compared with the contralateral pelvic limb.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Dogs with CCL disease were overweight compared with the control group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical significance<\/jats:title>\n                    <jats:p>Dogs that are overweight may be predisposed to developing CCL disease. Body composition changes in the pelvic limbs should be considered when managing the care of these dogs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vsu.13434","type":"journal-article","created":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T12:39:06Z","timestamp":1588336746000},"page":"1144-1153","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Body composition of medium to giant breed dogs with or without cranial cruciate ligament disease"],"prefix":"10.1111","volume":"49","author":[{"given":"Amanda","family":"Santarossa","sequence":"first","affiliation":[{"name":"Department of Clinical Studies Ontario Veterinary College, University of Guelph Guelph Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas W. G.","family":"Gibson","sequence":"additional","affiliation":[{"name":"Department of Clinical Studies Ontario Veterinary College, University of Guelph Guelph Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn","family":"Kerr","sequence":"additional","affiliation":[{"name":"Department of Clinical Studies Ontario Veterinary College, University of Guelph Guelph Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle J.","family":"Monteith","sequence":"additional","affiliation":[{"name":"Department of Clinical Studies Ontario Veterinary College, University of Guelph Guelph Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany","family":"Durzi","sequence":"additional","affiliation":[{"name":"Smith Lane Animal Hospital at Hill's Pet Nutrition Primary Healthcare Centre Ontario Veterinary College, University of Guelph Guelph Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Gowland","sequence":"additional","affiliation":[{"name":"Smith Lane Animal Hospital at Hill's Pet Nutrition Primary Healthcare Centre Ontario Veterinary College, University of Guelph Guelph Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adronie","family":"Verbrugghe","sequence":"additional","affiliation":[{"name":"Department of Clinical Studies Ontario Veterinary College, University of Guelph Guelph Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2010.00654.x"},{"key":"e_1_2_7_3_1","first-page":"350","volume-title":"BSAVA Manual of Canine and Feline Musculoskeletal Disorders","author":"McKee WM","year":"2006"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2010.00653.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3415\/VCOT-10-03-0030"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.232.12.1818"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.227.1604"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.2460\/javma.1993.203.07.1016","article-title":"Epidemiology of cranial cruciate ligament rupture in dogs","volume":"203","author":"Whitehair JG","year":"1993","journal-title":"J Am Vet Med Assoc."},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1632767"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2011.01073.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12349"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3415\/VCOT-10-04-0055"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-011-1755-y"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465030310061801"},{"key":"e_1_2_7_15_1","doi-asserted-by":"crossref","first-page":"811","DOI":"10.2460\/javma.1999.215.06.811","article-title":"Breed, sex, and body weight as risk factors for rupture of the cranial cruciate ligament in young dogs","volume":"215","author":"Duval JM","year":"1999","journal-title":"J Am Vet Med Assoc."},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1632506"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0396.2012.01336.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2002.220.1325"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.243.5.675"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.242.10.1364"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2013.12001.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055937"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2006.00159.x"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12593"},{"issue":"2","key":"e_1_2_7_25_1","first-page":"177","article-title":"Prevalence and risk factors for obesity in adult dogs from private US veterinary practices","volume":"4","author":"Lund EM","year":"2006","journal-title":"Int J Appl Res Vet Med."},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.163.17.503"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.240.12.1481"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2009.00532.x"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.234.2.229"},{"issue":"9","key":"e_1_2_7_30_1","first-page":"1","article-title":"Precision and practicality of methods assessing body composition of dogs and cats","volume":"23","author":"Burkholder WJ","year":"2001","journal-title":"Compend Contin Educ Vet."},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.251.5.521"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2010.00657.x"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1017\/S000711451100050X"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2007.00276.x"},{"key":"e_1_2_7_35_1","volume-title":"Small Animal Clinical Nutrition","author":"Hand MS","year":"2010"},{"issue":"4","key":"e_1_2_7_36_1","first-page":"10","article-title":"Development and validation of a body condition score system for dogs","volume":"22","author":"Laflamme DP","year":"1997","journal-title":"Canine Pract."},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2004.tb02607.x"},{"key":"e_1_2_7_38_1","first-page":"95","volume-title":"Advances in the Canine Cranial Cruciate Ligament","author":"Cook JL","year":"2011"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2010.04.004"},{"issue":"11","key":"e_1_2_7_40_1","first-page":"24","article-title":"Effect of adiponectin, leptin and visfatin on canine cranial cruciate ligament cells in terms of matrix degradation biomarkers","volume":"97","author":"Saengsoi W","year":"2015","journal-title":"Bone Joint J."},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.3415\/VCOT-08-08-0069"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2000.217.1678"},{"key":"e_1_2_7_43_1","volume-title":"Multimodal Management of Canine Osteoarthritis","author":"Fox SM","year":"2010"},{"key":"e_1_2_7_44_1","first-page":"1215","volume-title":"Small Animal Surgery","author":"Fossum TW","year":"2013"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/136.6.1453"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2002.220.1315"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114507871686"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(98)00046-5"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2001.62.1295"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2008.05.005"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0268-0890(05)80002-7"}],"container-title":["Veterinary Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vsu.13434","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vsu.13434","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vsu.13434","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,4]],"date-time":"2024-08-04T22:06:35Z","timestamp":1722809195000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vsu.13434"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":50,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1111\/vsu.13434"],"URL":"https:\/\/doi.org\/10.1111\/vsu.13434","archive":["Portico"],"relation":{},"ISSN":["0161-3499","1532-950X"],"issn-type":[{"value":"0161-3499","type":"print"},{"value":"1532-950X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"2019-07-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}