{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T01:50:14Z","timestamp":1792029014540,"version":"4.4.0"},"reference-count":37,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T00:00:00Z","timestamp":1594252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare in vitro knot holding strength of the laparoscopic Miller's knot (LMK), open Miller's knot (MK), open surgeon's throw (Sx), and laparoscopic surgeon's throw (LSx) in a vascular pedicle model when used as the first throw for vascular ligation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Experimental study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample population<\/jats:title><jats:p>Ten constructs each of the Miller's knot and surgeon's throw performed openly and laparoscopically with 2\u20100 polyglyconate suture.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Knot holding strengths of the LMK, MK, LSx, and Sx knots were evaluated on balloon dilation catheters used as vascular pedicle models. Laparoscopic knots were tied in a laparoscopic box trainer. Knot constructs were pressure tested to failure. Results were compared by Kruskal\u2010Wallis and Steel\u2010Dwass comparisons.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both MK and LMK had mean leakage pressures above 300\u2009mm Hg. The MK leaked at higher pressure than all other knots, including the LMK (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). The LMK leaked at greater pressures compared with the Sx and the LSx (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). No difference was detected between leaking pressures of the Sx and the LSx (<jats:italic>P<\/jats:italic> = .226), with both leaking at pressures below 40\u2009mm Hg.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The LMK created a more secure first throw compared with the Sx and leaked at supraphysiologic pressures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>The LMK has excellent knot holding strength on a vascular pedicle model and may be further evaluated for clinical application.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13479","type":"journal-article","created":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T16:10:34Z","timestamp":1594311034000},"page":"1563-1570","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["In vitro holding strength of the laparoscopic Miller's knot compared with open Miller's knot, open surgeon's throw, and laparoscopic surgeon's throw in a vascular pedicle model"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9214-3743","authenticated-orcid":false,"given":"Andrea K.","family":"Erickson","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine University of Florida  Gainesville Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Alexander","family":"Fox\u2010Alvarez","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine University of Florida  Gainesville Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penny J.","family":"Regier","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine University of Florida  Gainesville Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Brad","family":"Case","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine University of Florida  Gainesville Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2013.12025.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950x.2005.00041.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2015.08.002"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1308\/003588407X183418"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)63995-X"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1995.01430040101022"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12648"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6901"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1992.01420060094014"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12572"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2012.01076.x"},{"issue":"1","key":"e_1_2_9_13_1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.5005\/jp-journals-10007-1213","article-title":"Comparing extracorporeal knots in laparoscopy using knot and loop securities","volume":"7","author":"Rasaq AA","year":"2014","journal-title":"World J Laparosc Surg."},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1553350608316683"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-3804(05)80139-2"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-013-0596-3"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2018.01.032"},{"issue":"6","key":"e_1_2_9_18_1","first-page":"2123","article-title":"Commonly used suture materials in skin surgery","volume":"44","author":"Moy RL","year":"1991","journal-title":"Am Fam Physician."},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-002-8545-z"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019509-199604000-00011"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(95)80011-5"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.245.5.571"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1308\/003588414X13814021677638"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-010-1570-4"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2012.01260.x"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4160-2591-7.10006-2"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(16)45837-8"},{"issue":"1","key":"e_1_2_9_28_1","first-page":"17","article-title":"Intracorporeal knot\u2010tying and suturing techniques in laparoscopic surgery: technical details","volume":"4","author":"Croce E","year":"2000","journal-title":"JSLS."},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(01)01069-9"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.3109\/13645709709153075"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.73.2.302"},{"key":"e_1_2_9_32_1","volume-title":"The Ashley Book of Knots","author":"Ashley CW","year":"1993"},{"key":"e_1_2_9_33_1","article-title":"Surgery STAT: don't forget the Miller's knot","volume":"360","author":"Hardie RJ","year":"2008","journal-title":"DVM"},{"key":"e_1_2_9_34_1","article-title":"Creating a leak\u2010proof ligature with confidence. 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