{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T07:55:05Z","timestamp":1768809305897,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,8,11]],"date-time":"2020-08-11T00:00:00Z","timestamp":1597104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Birmingham Racing Commission; Department of Clinical Sciences of Auburn University."}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the biomechanical properties and healing of ventral midline celiotomies (VMC) closed with a self\u2010locking knot combination and forwarder start and Aberdeen end (F\u2010A) vs a traditional knot combination and surgeon's start and end (S\u2010S).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>In vivo, experimental.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Twenty\u2010one horses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fourteen horses underwent VMC, which was closed with either an F\u2010A (n = 7) or an S\u2010S (n = 7) knot combination. Incisions were subjectively graded by masked evaluators for dehiscence, edema, and drainage. Biomechanical testing was performed on three abdominal segments, and histology was performed on one segment from each animal after humane euthanasia 10\u2009days post\u2010VMC. The abdominal wall of control horses (n = 7, no celiotomy) was collected for biomechanical testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forwarder start and Aberdeen end and S\u2010S horses had less tensile strength compared with control horses (<jats:italic>P<\/jats:italic>\u2009\u2264\u2009.001). No differences were detected between treatment groups for any variable evaluated, including tensile strength (<jats:italic>P<\/jats:italic> = .975), location of failure (<jats:italic>P<\/jats:italic> = .240), and histologic healing at the knot (<jats:italic>P<\/jats:italic> = .600).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Closure of VMC with self\u2010locking knots resulted in biomechanical and healing features similar to those with a traditional closure technique, with neither restoring the tensile strength of the linea alba.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>Results of this study provide evidence to support a clinical trial to evaluate long\u2010term performance of the F\u2010A self\u2010locking knot closure in horses.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13497","type":"journal-article","created":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T02:39:50Z","timestamp":1597199990000},"page":"1580-1589","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Tensile strength and early healing of self\u2010locking and surgeon's knots"],"prefix":"10.1111","volume":"49","author":[{"given":"Kathleen M.","family":"Weatherall","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences Auburn University College of Veterinary Medicine  Auburn Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsey H.","family":"Boone","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Auburn University College of Veterinary Medicine  Auburn Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred J.","family":"Caldwell","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Auburn University College of Veterinary Medicine  Auburn Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert C.","family":"Cole","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Auburn University College of Veterinary Medicine  Auburn Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russell C.","family":"Cattley","sequence":"additional","affiliation":[{"name":"Department of Pathobiology Auburn University College of Veterinary Medicine  Auburn Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kara M.","family":"Lascola","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Auburn University College of Veterinary Medicine  Auburn Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart C.","family":"Clark\u2010Price","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Auburn University College of Veterinary Medicine  Auburn Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramsis","family":"Farag","sequence":"additional","affiliation":[{"name":"Center for Polymer and Advanced Composites Auburn University Samuel Ginn College of Engineering  Auburn Alabama USA"},{"name":"Department of Textile Engineering Mansoura University  Mansoura Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edmon","family":"Perkins","sequence":"additional","affiliation":[{"name":"Department of Mechanical and Aerospace Engineering North Carolina State University  Raleigh North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. 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