{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:21:08Z","timestamp":1790623268761,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T00:00:00Z","timestamp":1617753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To identify demographic risk factors for deep surgical site infection (SSI) requiring tibial plateau leveling osteotomy (TPLO) implant removal and time to implant removal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Four hundred and thirty\u2010three dogs that underwent a TPLO (144 that developed a deep SSI and required implant removal, 289 that did not).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective case\u2013control study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Records of dogs undergoing implant removal due to a deep SSI after TPLO between 2006 and 2018 at two referral centers were reviewed. These records were frequency\u2010matched by date to dogs undergoing TPLO that did not require implant removal. Multivariable analyses tested associations between demographics and implant removal as well as timing of implant removal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Deep SSI and implant removal occurred in 144 of 4813 (3.0%; 95% CI: 2.5, 3.5) dogs treated with TPLO. Implant removal was performed at a median of 279\u2009days (range 49\u20132394\u2009days) postoperatively. Male dogs (OR 1.8; 95% CI: 1.2, 2.7) and German Shepherd dogs (GSDs) (OR 7.4; 95% CI: 2.6, 20.5) were associated with plate removal. Earlier TPLO plate removal was associated with GSDs only (HR 2.4; 95% CI: 1.4, 4.1).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Implant removal due to SSI after TPLO was uncommon, although male dogs and GSDs seemed predisposed to this complication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>These demographic risk factors can be used to educate owners regarding perioperative management.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13634","type":"journal-article","created":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T14:04:20Z","timestamp":1617804260000},"page":"999-1008","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Timing of and risk factors for deep surgical site infection requiring implant removal following canine tibial plateau leveling osteotomy"],"prefix":"10.1111","volume":"50","author":[{"given":"Renee A.","family":"McDougall","sequence":"first","affiliation":[{"name":"Department of Surgery The Animal Medical Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel I.","family":"Spector","sequence":"additional","affiliation":[{"name":"Department of Surgery The Animal Medical Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert C.","family":"Hart","sequence":"additional","affiliation":[{"name":"Department of Surgery The Animal Medical Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.","family":"Dycus","sequence":"additional","affiliation":[{"name":"Department of Surgery Veterinary Orthopedics and Sports Medicine Group  Annapolis Junction Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hollis N.","family":"Erb","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine Cornell University  Ithaca New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,4,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.5326\/0400385"},{"key":"e_1_2_8_3_1","first-page":"1209","volume-title":"Current Techniques in Small Animal Surgery","author":"Slocum B","year":"1998"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2007.00361.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2003.222.184"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2003.222.1726"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.5326\/0420044"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2013.12048.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2010.00663.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1988.tb00278.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.242.3.355"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2014.12269.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3415\/VCOT-11-12-0177"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2012.00971.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2013.12001.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2014.12175.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.3415\/VCOT-10-12-0172"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.253.3.315"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.247.8.909"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12958"},{"key":"e_1_2_8_21_1","unstructured":"National Healthcare Safety Network patient safety component manual: chapter 9: surgical site infection (SSI) event. Centers for Disease Control and Prevention Web site.https:\/\/www.cdc.gov\/nhsn\/PDFs\/pscManual\/9pscSSIcurrent.pdf. Accessed March 10 2021."},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2013.2925"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpb.2018.01.008"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2013.04.073"},{"key":"e_1_2_8_25_1","first-page":"249","article-title":"Complications associated with tibial plateau leveling osteotomy: a retrospective of 1519 procedures","volume":"55","author":"Coletti TJ","year":"2014","journal-title":"Can Vet J"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12796"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2014.12212.x"},{"key":"e_1_2_8_28_1","first-page":"229","article-title":"Comparison of complications following tibial tuberosity advancement and tibial plateau levelling osteotomy in very large and giant dogs 50 kg or more in body weight","volume":"30","author":"Hans EC","year":"2017","journal-title":"Vet Comp Orthop Traumatol"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI0215704"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1550-8579(07)80061-1"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12407"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.103688"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13337"}],"container-title":["Veterinary Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vsu.13634","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vsu.13634","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vsu.13634","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T18:07:10Z","timestamp":1693332430000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vsu.13634"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,7]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1111\/vsu.13634"],"URL":"https:\/\/doi.org\/10.1111\/vsu.13634","archive":["Portico"],"relation":{},"ISSN":["0161-3499","1532-950X"],"issn-type":[{"value":"0161-3499","type":"print"},{"value":"1532-950X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,7]]},"assertion":[{"value":"2020-06-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}