{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T14:22:04Z","timestamp":1760710924118},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,3,16]],"date-time":"2022-03-16T00:00:00Z","timestamp":1647388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To report the incidence of short\u2010term incisional complications in dogs receiving intraoperative local infiltration of liposomal bupivacaine.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Retrospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Client\u2010owned dogs (<jats:italic>n<\/jats:italic>\u00a0=\u00a0218).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records were searched for dogs whose surgical site was infiltrated with liposomal bupivacaine. Records were reviewed for complications within 20\u2009days postoperatively. Cases were categorized by: (1) surgical wound classification (clean, clean\u2010contaminated, contaminated); (2) labeled versus off\u2010label use in orthopedic surgery \u2013 stifle surgery to address cranial cruciate ligament (CCL) disease versus other orthopedic procedures; and (3) orthopedic versus soft\u2010tissue surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Complications were documented in 43\/218 (19.7%) records, including 27\/218 (12.4%) complications that resolved spontaneously or with topical treatment. The incidence of short\u2010term incisional complications did not differ between surgical wound classifications (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.55) or between labeled versus off\u2010label use in orthopedic surgery (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.21). Complications seemed more common after soft\u2010tissue procedures (32\/123; 26.0%) than orthopedic procedures (11\/95; 11.6%) (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Surgical wound classification or type of orthopedic procedure did not seem to influence incisional complications of infiltrated surgical sites. Complications were more common after soft\u2010tissue procedures than orthopedic procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>Infiltration of surgical sites with liposomal bupivacaine seems safe in a broader range of orthopedic procedures than currently labeled. The results also justify further investigation in soft\u2010tissue surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13803","type":"journal-article","created":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T06:45:25Z","timestamp":1647499525000},"page":"674-681","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Incidence and severity of short\u2010term incisional complications after intraoperative local infiltration of liposomal bupivacaine in dogs"],"prefix":"10.1111","volume":"51","author":[{"given":"Ashley M.","family":"Power","sequence":"first","affiliation":[{"name":"VCA South Shore Animal Hospital  Weymouth Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Talon","family":"McKee","sequence":"additional","affiliation":[{"name":"VCA Clinical Studies  California Los Angeles USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kara","family":"Jordan","sequence":"additional","affiliation":[{"name":"VCA South Shore Animal Hospital  Weymouth Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip J.","family":"Bergman","sequence":"additional","affiliation":[{"name":"VCA Clinical Studies  California Los Angeles USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kechia M.","family":"Davis","sequence":"additional","affiliation":[{"name":"VCA South Shore Animal Hospital  Weymouth Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,16]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"Nocita Technical Monograph. 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