{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:31:06Z","timestamp":1790742666040,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T00:00:00Z","timestamp":1664236800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the 6\u2010month outcome and survival of enhanced polyethylene terephthalate (PET) implants as a replacement for the cranial cruciate ligament (CCL) in dogs with spontaneous CCL disease (CCLD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Pilot, prospective case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Ten client\u2010owned large breed dogs with unilateral spontaneous CCLD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Dogs were evaluated before and 6\u00a0months after intra\u2010articular placement of a PET implant with the Liverpool Osteoarthritis in Dogs questionnaire and force platform gait analysis. Arthroscopy was performed 6\u00a0months after surgery to visually assess implant integrity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Scores on owner questionnaires and limb asymmetry improved in all dogs that reached the 6\u2010month time point, by 51.7% (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.008) and 86% (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.002), respectively. The PET implant appeared intact and functioning in two stifles, partially intact and functioning in four stifles and completely torn in three stifles. One dog had an implant infection and was removed from the study. Evidence of deterioration and tearing occurred in the midbody of the implant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although function improved over the course of this study, only 2\/10 implants appeared intact 6\u00a0months after placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>Implant survivability prohibits further clinical investigation using this implant.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13889","type":"journal-article","created":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T10:50:01Z","timestamp":1664275801000},"page":"1215-1222","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Outcome of cranial cruciate ligament replacement with an enhanced polyethylene terephthalate implant in the dog: A pilot clinical trial"],"prefix":"10.1111","volume":"51","author":[{"given":"Tiffany A.","family":"Johnson","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences University of Minnesota, College of Veterinary Medicine  Saint Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Conzemius","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences University of Minnesota, College of Veterinary Medicine  Saint Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.226.232"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.243.5.675"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2012.01052.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2013.12033.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.242.10.1364"},{"key":"e_1_2_8_7_1","first-page":"1095","article-title":"Comparison of radiographic osteoarthritis scores in dogs less than 24 months or greater than 24 months following tibial plateau leveling osteotomy","volume":"53","author":"DeLuke AM","year":"2012","journal-title":"Can Vet J"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2010.00663.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13356"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13634"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12653"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13379"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0160(00)00039-9"},{"issue":"1","key":"e_1_2_8_14_1","first-page":"113","article-title":"Comparison of results of ACL reconstruction using LARS method and autogenous ST\/GR graft","volume":"21","author":"P\u0142ocki J","year":"2019","journal-title":"Acta Bioeng Biomech"},{"issue":"5","key":"e_1_2_8_15_1","first-page":"542","article-title":"Effectiveness of patellar tendon reconstruction with LARS artificial ligament for old patellar tendon rupture","volume":"33","author":"Yang Y","year":"2019","journal-title":"Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi"},{"key":"e_1_2_8_16_1","first-page":"e101","article-title":"Medium\u2010term (least 5\u2009years) comparative outcomes in anterior cruciate ligament reconstruction using 4SHG, allograft, and LARS ligament","author":"Su M","year":"2019","journal-title":"Clin J Sport Med"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-018-2304-x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-019-05478-3"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2013.02.025"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3415\/VCOT-15-12-0206"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.76.5.411"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-matsci-070214-020815"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.34928"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.35218"},{"key":"e_1_2_8_25_1","first-page":"29","article-title":"Anterior cruciate ligament reconstruction: a look at prosthetics \u2010 past, present and possible future","volume":"11","author":"Mascarenhas R","year":"2008","journal-title":"McGill J Med"},{"key":"e_1_2_8_26_1","unstructured":"GadomskiBC LabusKM McGilvrayKM NelsonB PalmerB StewartH PuttlitzCM EasleyJ. \u201cDevelopment of a novel resorbable interference screw for tendon attachment.\u201d 65th Annual Meeting of the Orthopedic Research Society; Phoenix AZ 2020. 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