{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T19:41:31Z","timestamp":1787946091056,"version":"build-2784847793"},"reference-count":55,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,3,7]],"date-time":"2023-03-07T00:00:00Z","timestamp":1678147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the effects of ala vestibuloplasty on cardiopulmonary and lifestyle\u2010related parameters in brachycephalic (BC) cats.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Prospective cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Client\u2010owned BC cats (<jats:italic>n<\/jats:italic>\u00a0=\u00a019).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cats were assessed preoperatively by airway computed tomography (CT), endoscopy, contrast echocardiography, cardiac biomarkers, and structured owner questionnaire. Ala vestibuloplasty was performed bilaterally, and blood values, imaging, and owner questionnaire responses were re\u2010evaluated 8\u201020\u2009weeks postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cats were presented for predominantly respiratory clinical signs attributable to brachycephaly. Preoperatively, all cats had stenotic nares, prolonged normalized pulmonary transit time (nPTT) (mean 5.43\u2009\u00b1\u20091.10\u00a0s), and a hyperattenuating pulmonary pattern. No complications occurred following surgery. Postoperatively, nPTT (mean 3.89\u2009\u00b1\u20090.74\u2009s,<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and frequencies of sneezing (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.002), snoring (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.006), open\u2010mouth breathing (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.0004), and nasal discharge (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.019) were decreased. Cats exhibited increased activity (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.005), less frequent dyspnea during activity (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), longer duration of activity before becoming dyspneic (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.002), faster recovery from activity (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), and decreased respiratory noise (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). Median questionnaire scores improved from preoperative to postoperative (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Anatomic, echocardiographic, and CT changes were common in this cohort of clinically affected BC cats. Pulmonary blood flow and respiratory function were improved after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>Stenotic nares are the predominant airway abnormality in BC cats. Ala vestibuloplasty is a safe procedure that improves cardiac and CT abnormalities and respiratory and other clinical signs in BC cats.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.13948","type":"journal-article","created":{"date-parts":[[2023,3,7]],"date-time":"2023-03-07T23:23:36Z","timestamp":1678231416000},"page":"575-586","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Ala vestibuloplasty improves cardiopulmonary and activity\u2010related parameters in brachycephalic cats"],"prefix":"10.1111","volume":"52","author":[{"given":"Hadley E.","family":"Gleason","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Medicine, College of Veterinary Medicine University of Illinois Urbana Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3291-0266","authenticated-orcid":false,"given":"Heidi","family":"Phillips","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Medicine, College of Veterinary Medicine University of Illinois Urbana Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Fries","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Medicine, College of Veterinary Medicine University of Illinois Urbana Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Keating","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Medicine, College of Veterinary Medicine University of Illinois Urbana Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip","family":"Hamel","sequence":"additional","affiliation":[{"name":"Boundary Bay Veterinary Specialty Hospital Langley British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4088-6902","authenticated-orcid":false,"given":"Annette","family":"McCoy","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Medicine, College of Veterinary Medicine University of Illinois Urbana Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2009.08.033"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.237.9.1048"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0161777"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0264.2003.00448.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.09.010"},{"issue":"1","key":"e_1_2_9_7_1","first-page":"31","article-title":"Surgical\u2010correction of stenotic nares in a cat","volume":"22","author":"Harvey CE","year":"1986","journal-title":"J Am Anim Hosp Assoc"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13302"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12446"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12447"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2008.09.009"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0181928"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.15547"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.5326\/JAAHA-MS-6281"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12734"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.5326\/JAAHA-MS-6654"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2012.00941.x"},{"issue":"1","key":"e_1_2_9_18_1","first-page":"58","article-title":"Clinical assessment and C\u2010reactive protein (CRP), haptoglobin (Hp), and cardiac troponin I (cTnI) values of brachycephalic dogs with upper airway obstruction before and after surgery","volume":"79","author":"Planellas M","year":"2015","journal-title":"Can J Vet Res"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.5326\/0460366"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13931"},{"key":"e_1_2_9_21_1","article-title":"Stenotic nares surgery in brachycephalic dogs","volume":"18","author":"Harvey CE","year":"1982","journal-title":"J Am Anim Hosp Assoc"},{"key":"e_1_2_9_22_1","article-title":"Upper airway obstruction surgery. 2. 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