{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T03:21:29Z","timestamp":1787887289365,"version":"build-2784847793"},"reference-count":48,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,12,10]],"date-time":"2023-12-10T00:00:00Z","timestamp":1702166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the intraluminal initial and maximal pressures of enterotomies closed using three different techniques (single\u2010layer appositional continuous closure; closure with cyanoacrylate; a single\u2010layer appositional closure augmented with cyanoacrylate) in a cooled canine cadaveric jejunal model and to report the initial leak location in all samples.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Experimental, ex\u2010vivo study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample population<\/jats:title><jats:p>Grossly normal chilled small intestine segments from three canine cadavers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 45 chilled jejunal segments (<jats:italic>n<\/jats:italic>\u2009=\u200915\u2009segments\/group) were assigned to a handsewn group (HSE), a cyanoacrylate only group (CE) and a handsewn and cyanoacrylate group (HS\u2009+\u2009CE). A 2\u2009cm antimesenteric enterotomy was performed and closure with one of the above techniques. Initial leakage pressures (ILP), maximal intraluminal pressures (MIP) and initial leakage location were recorded by a single observer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Handsewn enterotomies leaked at higher ILP when augmented with cyanoacrylate (83.3\u2009\u00b1\u20094.6\u2009mmHg, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) compared to both the HSE group (43.8\u2009\u00b1\u20095.3\u2009mmHg) and the CE group (18.6\u2009\u00b1\u20093.5\u2009mmHg). Those sealed with cyanoacrylate only leaked at a lower MIP compared with the other groups (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). Maximal intraluminal pressures did not differ between handsewn enterotomies, whether augmented or not (<jats:italic>p<\/jats:italic>\u2009=\u2009.19).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Reinforcement of a sutured enterotomy closure with cyanoacrylate was easy to perform and resulted in significantly increased initial leak pressures in cadaveric jejunum.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>The increased leakage pressures achieved by reinforcing enterotomies with cyanoacrylate could consequently reduce the incidence of postoperative intestinal leakage following an enterotomy and may result in reduced patient morbidity or mortality.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.14059","type":"journal-article","created":{"date-parts":[[2023,12,10]],"date-time":"2023-12-10T18:29:52Z","timestamp":1702232992000},"page":"367-375","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of cyanoacrylate on leakage pressures of cooled canine cadaveric jejunal enterotomies"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6634-7926","authenticated-orcid":false,"given":"Jamie\u2010Leigh","family":"Thompson","sequence":"first","affiliation":[{"name":"Department of Small Animal Surgery The Royal Dick School of Veterinary Studies  Edinburgh Scotland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Analgesia The Royal Dick School of Veterinary Studies  Edinburgh Scotland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6482-7224","authenticated-orcid":false,"given":"Kelly","family":"Bowlt Blacklock","sequence":"additional","affiliation":[{"name":"Department of Small Animal Surgery The Royal Dick School of Veterinary Studies  Edinburgh Scotland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2005.tb00326.x"},{"key":"e_1_2_9_3_1","first-page":"469","article-title":"Mortality and morbidity of small and large intestinal surgery in dogs and cats: 74 cases (1980\u20131992)","volume":"30","author":"Wylie KB","year":"1994","journal-title":"J Am Anim Hosp Assoc"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.238.4.486"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2009.00790.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-37-1-87"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2003.223.73"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2011.05.006"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12413"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01062909"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vaa.12093"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13339"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(05)80977-1"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(05)70596-X"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.31368"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2011.12.003"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0157920"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-012-2156-0"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10353-015-0367-z"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10029-018-1861-6"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10029-020-02144-3"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2005.00011.x"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12047"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13044"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani13172732"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(83)90144-7"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcam.2020.100457"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.74.8.1138"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13274"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13451"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13827"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13392"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.2017.1344586"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000181809.51544.20"},{"key":"e_1_2_9_35_1","first-page":"121","article-title":"Adhesivo tisular 2\u2010octil cianoacrilato en el cierre de enterotom\u00eda comparado con sutura manual tradicional en dos capas. Modelo en Perros","volume":"77","author":"Escalante\u2010Pi\u00f1a O","year":"2009","journal-title":"Cir Ciruj"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-69912011000100009"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.79.12.1335"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2014.06.002"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2006.02.022"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2006.02.038"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2009.11.016"},{"key":"e_1_2_9_42_1","first-page":"E124","article-title":"Endoscopic ultrasound\u2010guided angiotherapy in bleeding gastrointestinal stromal tumors with coil deployment and cyanoacrylate injection","volume":"53","author":"Romero\u2010Castro R","year":"2020","journal-title":"Endoscopy"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2019.05.019"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtos.2020.08.001"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-1123-9054"},{"issue":"2","key":"e_1_2_9_46_1","first-page":"115","article-title":"Comparison of n butyl 2 cyanoacrylate and silk sutures for minor surgical procedure: a clinical study","volume":"8","author":"Jamdar S","year":"2020","journal-title":"J Adv Med Dent Sci Res"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(00)01075-X"},{"issue":"2","key":"e_1_2_9_48_1","first-page":"103","article-title":"Adhesivo tisular 2\u2010cianoacrilato de n\u2010butilo en el cierre de perforaci\u00f3n vesical comparado con sutura en dos capas; modelo en perros","volume":"70","author":"D\u00e1vila\u2010Serapio F","year":"2010","journal-title":"Rev Mex Urol"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.71.3.370"}],"container-title":["Veterinary Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vsu.14059","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T12:24:13Z","timestamp":1713270253000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vsu.14059"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,10]]},"references-count":48,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1111\/vsu.14059"],"URL":"https:\/\/doi.org\/10.1111\/vsu.14059","archive":["Portico"],"relation":{},"ISSN":["0161-3499","1532-950X"],"issn-type":[{"value":"0161-3499","type":"print"},{"value":"1532-950X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,10]]},"assertion":[{"value":"2023-03-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}