{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T16:58:28Z","timestamp":1780678708270,"version":"3.54.1"},"reference-count":58,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T00:00:00Z","timestamp":1717545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess a three\u2010dimensional (3\u2010D)\u2010printed laryngeal clamp (LC) designed to enhance the anchoring of laryngeal prostheses at the cricoid cartilage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Ex vivo biomechanical study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample population<\/jats:title><jats:p>A total of 22 equine larynges.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two experimental groups included larynges with standard prosthetic laryngoplasty (PL; <jats:italic>n<\/jats:italic>\u2009=\u200910) and larynges with prosthetic laryngoplasty modified with laryngeal clamps (PLLC; <jats:italic>n<\/jats:italic>\u2009=\u200910). All constructs underwent 3000\u2009cycles of tension loading and a single tension to failure. Recorded biomechanical parameters included maximum load, actuator displacement, and construct failure. Finite element analysis (FEA) was performed on one PL and one PLLC construct.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The maximum load at single tension to failure was 183.7\u2009\u00b1\u200946.8\u2009N for the PL construct and 292.7\u2009\u00b1\u200982.3\u2009N for the PLLC construct (<jats:italic>p<\/jats:italic>\u2009=\u2009.003). Actuator displacement at 30\u2009N was 1.7\u2009\u00b1\u20090.5\u2009mm and 2.7\u2009\u00b1\u20090.7\u2009mm for the PL and PLLC constructs, respectively (<jats:italic>p<\/jats:italic>\u2009=\u2009.011). The cause of PL constructs failure was mostly tearing through the cartilage whereas the PLLC constructs failed through fracture of the cricoid cartilage (<jats:italic>p<\/jats:italic>\u2009=\u2009.000). FEA revealed an 11\u2010fold reduction in the maximum equivalent plastic strain, a four\u2010fold reduction in maximum compressive stress, and a two\u2010fold increase in the volume of engaged cartilage in PLLC constructs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The PLLC constructs demonstrated superior performance in biomechanical testing and FEA compared to standard PL constructs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>The use of 3\u2010D\u2010printed laryngeal clamps may enhance the outcomes of laryngoplasty in horses. In vivo studies are necessary to determine the feasibility of performing laryngoplasty using the laryngeal clamp in horses.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.14115","type":"journal-article","created":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T05:40:30Z","timestamp":1717652430000},"page":"1161-1172","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Enhancing prosthesis stability at the cricoid cartilage in equine laryngoplasty using <scp>3\u2010D<\/scp>\u2010printed laryngeal clamps: An ex vivo model study"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8656-5162","authenticated-orcid":false,"given":"Remigiusz","family":"Grzeskowiak","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine, Large Animal Clinical Sciences The University of Tennessee  Knoxville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0073-5897","authenticated-orcid":false,"given":"Jim","family":"Schumacher","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Large Animal Clinical Sciences The University of Tennessee  Knoxville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omid","family":"Omidi","sequence":"additional","affiliation":[{"name":"Tickle College of Engineering, Mechanical, Aerospace and Biomedical Engineering The University of Tennessee  Knoxville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin","family":"Bowers","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Large Animal Clinical Sciences The University of Tennessee  Knoxville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynne M. C.","family":"Cassone","sequence":"additional","affiliation":[{"name":"College of Agriculture, Food and Environment, Veterinary Diagnostic Laboratory The University of Kentucky  Lexington Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Abedi","sequence":"additional","affiliation":[{"name":"Tickle College of Engineering, Mechanical, Aerospace and Biomedical Engineering The University of Tennessee  Knoxville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9060-2309","authenticated-orcid":false,"given":"Adrien\u2010Maxence","family":"Hespel","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Small Animal Clinical Sciences The University of Tennessee  Knoxville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8722-4370","authenticated-orcid":false,"given":"Pierre\u2010Yves","family":"Mulon","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Large Animal Clinical Sciences The University of Tennessee  Knoxville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0745-7591","authenticated-orcid":false,"given":"David E.","family":"Anderson","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Large Animal Clinical Sciences The University of Tennessee  Knoxville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2006.00192.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516401776254790"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/avj.12620"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516406778400583"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042\u20103306.2010.00033.x"},{"issue":"2","key":"e_1_2_10_7_1","first-page":"157","article-title":"Use of a prosthetic device for surgical correction of laryngeal hemiplegia in horses","volume":"157","author":"Marks D","year":"1970","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.150.15.481"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/jvet.2001.25865"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516408x343163"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12331"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516403776014172"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.2746\/0425164044868440"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2009.00600.x"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2010.00746.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2013.01109.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2012.01061.x"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.1990.51.01.114"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042\u20103306.2010.00070.x"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.12131"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2008.00423.x"},{"key":"e_1_2_10_22_1","first-page":"115","article-title":"Arytenoid cartilage retention of laryngoplasty in horses\u2014in vitro assessment of effect of age, placement site and implantation technique","volume":"47","author":"Herde I","year":"2001","journal-title":"Proc Am Assoc Equine Pract"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2010.00701.x"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12933"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13137"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.79.2.226"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2014.12184.x"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12671"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12659"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516400777611991"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2014.12248.x"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2005.00086.x"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2020.601244"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JHSB.2006.03.162"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.32098\/mltj.03.2013.16"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2010.06.002"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2002.12.001"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200001)43:1<215::AID-ANR26>3.0.CO;2-X"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546512472168"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513499228"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/term.2847"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2020.00139"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1114\/1.1561287"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.4000991"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042\u20103306.2010.00315.x"},{"issue":"4","key":"e_1_2_10_46_1","first-page":"307","article-title":"Equine cricoid cartilage densitometry","volume":"57","author":"Behrens E","year":"1993","journal-title":"Can J Vet Res"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2010.00742.x"},{"key":"e_1_2_10_48_1","volume-title":"Biomechanics for Surgeons","author":"Smith G","year":"1993"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.75.5.500"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmps.2012.10.004"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2006.06.013"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/jam.14290"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1010\u20105182(98)80045\u20100"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/biot.201000135"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.200500062"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2016.03.012"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.TEA.2016.0418"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2004.04.031"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24244532"}],"container-title":["Veterinary Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vsu.14115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T03:27:24Z","timestamp":1729567644000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vsu.14115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,5]]},"references-count":58,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1111\/vsu.14115"],"URL":"https:\/\/doi.org\/10.1111\/vsu.14115","archive":["Portico"],"relation":{},"ISSN":["0161-3499","1532-950X"],"issn-type":[{"value":"0161-3499","type":"print"},{"value":"1532-950X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,5]]},"assertion":[{"value":"2024-02-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}