{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T07:44:37Z","timestamp":1763106277088,"version":"3.45.0"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T00:00:00Z","timestamp":1734652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine the influence on surgical site infection (SSI) rates when using 0.7% iodophor and 74% isopropyl alcohol versus 2% chlorhexidine and 70% isopropyl alcohol. To evaluate the adherence of an iodophor\u2010impregnated surgical incise drape when used in conjunction with 0.7% iodophor and 74% isopropyl alcohol.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Combines retrospective control and prospective data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Sample population<\/jats:title>\n                    <jats:p>This study included dogs and cats, 653 retrospective cases and 435 prospective cases, with 447 incisions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The SSI rate of a 2% chlorhexidine and 70% isopropyl alcohol preparation was retrospectively reviewed. The prospective population received 0.7% iodophor and 74% isopropyl alcohol; risk factors for SSI were evaluated and incise drape lift was documented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A 1.8% difference in SSI between the chlorhexidine group and 0.7% iodophor and 74% isopropyl alcohol group was found (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.25). The drape lift was 13.2%. Drape lift (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.026), increased body weight (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.008), and the use of glutaraldehyde for instrument sterilization (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.055) were associated with an increased risk of SSI development.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The 0.7% iodophor and 74% isopropyl alcohol treatments demonstrated similar effectiveness to 2% chlorhexidine and 70% isopropyl alcohol in skin preparation. Using an iodophor\u2010impregnated drape with 0.7% iodophor and 74% isopropyl alcohol reduced both drape lift and the risk of SSI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical significance<\/jats:title>\n                    <jats:p>These findings support the combined use of an incise drape with 0.7% iodophor and 74% isopropyl alcohol preparation, provide evidence against the use of glutaraldehyde, and indicate that heavier patients have an increased risk of SSI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vsu.14198","type":"journal-article","created":{"date-parts":[[2024,12,21]],"date-time":"2024-12-21T02:34:28Z","timestamp":1734748468000},"page":"478-485","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Influence of skin preparation on surgical site infection and lift of adhesive surgical drapes"],"prefix":"10.1111","volume":"54","author":[{"given":"James W.","family":"Gant","sequence":"first","affiliation":[{"name":"Metropolitan Veterinary Hospital  Akron Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josh E.","family":"Collins","sequence":"additional","affiliation":[{"name":"Metropolitan Veterinary Hospital  Akron Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zachary A.","family":"Miller","sequence":"additional","affiliation":[{"name":"Metropolitan Veterinary Hospital  Akron Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard L.","family":"Einsporn","sequence":"additional","affiliation":[{"name":"The University of Akron  Akron Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,12,20]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"CDC.Surgical Site Infections Event.2024https:\/\/www.cdc.gov\/nhsn\/pdfs\/pscmanual\/9pscssicurrent.pdf. 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