{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T21:42:57Z","timestamp":1763415777504,"version":"3.41.2"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,5,11]],"date-time":"2025-05-11T00:00:00Z","timestamp":1746921600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To report 30\u2010day survival of cats that experienced postattenuation neurologic signs (PANS) after surgical attenuation of a single congenital portosystemic shunt (cPSS), and to investigate prognostic factors for short\u2010term survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Multi\u2010institutional retrospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample population<\/jats:title><jats:p>A total of 59 cats with cPSS that experienced PANS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The medical records of 10 institutions were retrospectively reviewed to identify cats that underwent cPSS attenuation from January 1, 2010 through June 30, 2023 and developed PANS within 7\u2009days postoperatively. Exclusion criteria were cats with arteriovenous malformation and cats lost\u2010to\u2010follow\u2010up prior to 30\u2009days. Logistic regression identified factors associated with 30\u2010day survival. Odds Ratios (OR) and 95% CIs were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 46 (78.0%) PANS\u2010affected cats survived to 30\u2009days. A total of 13 (50.0%) of 26 cats that experienced postattenuation seizures (PAS) survived to 30\u2009days, with most non\u2010surviving cats experiencing generalized PAS. Cats that experienced PAS (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01, OR: 0.015, 95% CI: &lt;0.001\u20130.281) and treatment of PANS with propofol (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01, OR: 0.112, 95% CI: 0.022\u20130.569) were associated with decreased odds of 30\u2010day survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Most cats that experienced PANS survived to 30\u2009days; however, short\u2010term survival rate was worse for cats that experienced PAS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>The prognosis for cats that experience PANS is generally good but experiencing PAS and requiring treatment with propofol are negative prognostic factors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vsu.14267","type":"journal-article","created":{"date-parts":[[2025,5,11]],"date-time":"2025-05-11T03:09:44Z","timestamp":1746932984000},"page":"930-944","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prognostic factors for short\u2010term survival of cats that experienced postattenuation neurologic signs after surgical attenuation of single congenital portosystemic shunts"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3091-1393","authenticated-orcid":false,"given":"Ignacio","family":"Otero Balda","sequence":"first","affiliation":[{"name":"Department of Small Animal Surgery, Small Animal Clinical Studies Section, School of Veterinary Medicine, College of Health and Agricultural Sciences University College Dublin  Dublin 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J.","family":"Lipscomb","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Services Royal Veterinary College  Hatfield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Kummeling","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University  Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5070-8176","authenticated-orcid":false,"given":"Nausikaa","family":"Devriendt","sequence":"additional","affiliation":[{"name":"Small Animal Department, Faculty of Veterinary Medicine Ghent University  Merelbeke Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8087-256X","authenticated-orcid":false,"given":"Hilde","family":"de Rooster","sequence":"additional","affiliation":[{"name":"Small Animal Department, Faculty of Veterinary Medicine Ghent 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