{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T01:26:06Z","timestamp":1763169966093,"version":"3.45.0"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To report the outcome of a dog with severe mitral regurgitation (MR) treated with open\u2010heart surgery using the modified taut\u2010line hitch (modified TLH) knot technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 9\u2010year\u2010old, 8.8\u2010kg intact male Cavalier King Charles Spaniel was referred for clinical signs of congestive heart failure secondary to severe mitral regurgitation. The dog underwent mitral valve repair under cardiopulmonary bypass. On echocardiographic examination, the left atrial\u2010to\u2010aortic root ratio (LA\/Ao) was 2.87, and the normalized left ventricular internal diameter in diastole (LVIDdN) was 2.43. After cardiac arrest, semi\u2010circular suture annuloplasty and chordal reconstruction using ePTFE sutures were performed. Artificial chordae lengths were adjusted using the modified TLH knot technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Vertebral heart scores (VHS) were 15.0 (preoperatively), 12.0 (3 months), 12.3 (6 months) and 12.6 (1\u2009year). LVIDd values were 46.1\u2009mm (preoperatively), 33.3\u2009mm (3 months), 34.1\u2009mm (6 months) and 37.1\u2009mm (1\u2009year). LA\/Ao ratios were 2.87 (preoperatively), 1.78 (3 months), 1.90 (6 months) and 1.97 (1\u2009year). The patient remained on pimobendan (0.25\u2009mg\/kg every 12\u2009h) at the intermediate\u2010term follow\u2010up, and from the 1\u2010year evaluation, furosemide (2\u2009mg\/kg once daily) was prescribed in addition to pimobendan. At the long\u2010term follow\u2010up, no clinical signs of congestive heart failure were observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Mitral valve repair using the modified TLH knot technique was associated with control of clinical signs and a reduction in medical therapy requirements during long\u2010term follow\u2010up in a dog with severe MR.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vsu.70011","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T07:41:23Z","timestamp":1756885283000},"page":"1616-1624","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mitral valve repair in a dog with a modified taut\u2010line hitch knot technique"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3791-7176","authenticated-orcid":false,"given":"Murat","family":"Vurucu","sequence":"first","affiliation":[{"name":"Department of Small Animal Cardiovascular Surgery Izmir Animal Hospital  Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aykut","family":"Cokogullu","sequence":"additional","affiliation":[{"name":"Department of Small Animal Cardiovascular Surgery Izmir Animal Hospital  Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bugra","family":"Ozcan","sequence":"additional","affiliation":[{"name":"Department of Small Animal Cardiovascular Surgery Izmir Animal Hospital  Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.240.10.1194"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.226.1508"},{"key":"e_1_2_8_4_1","article-title":"Mitral valve replacement with a mechanical valve for severe mitral regurgitation in a small dog","volume":"1","author":"Taguchi D","year":"2014","journal-title":"Case Rep Vet Med"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.20.09.0519"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2012.01.004"},{"issue":"3","key":"e_1_2_8_7_1","first-page":"III30","article-title":"Ten\u2010year experience of chordal replacement with expanded polytetrafluoroethylene in mitral valve repair","volume":"102","author":"Kobayashi J","year":"2000","journal-title":"Circulation"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1749-8090-5-22"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1556984520901487"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani12131653"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11748-021-01664-8"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)39144-5"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-12-1600"},{"key":"e_1_2_8_14_1","first-page":"1","article-title":"Mitral valve annuloplasty and chordal replacement in dogs","volume":"4","author":"Uechi M","year":"2020","journal-title":"J\u2010Stage"},{"key":"e_1_2_8_15_1","unstructured":"UechiM.Surgical and interventional approaches to MMVD. International Cardiology Veterinary Symposium.2016(Abstract)."},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.4081\/vsd.2017.6335"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.11-0486"},{"key":"e_1_2_8_18_1","first-page":"175","volume-title":"Advances in Mitral Valve Repair for Degenerative Mitral Regurgitation","author":"Forno B","year":"2021"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2004.224.1941"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.4081\/vsd.2017.6442"}],"container-title":["Veterinary Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vsu.70011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T01:22:56Z","timestamp":1763169776000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vsu.70011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,3]]},"references-count":19,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1111\/vsu.70011"],"URL":"https:\/\/doi.org\/10.1111\/vsu.70011","archive":["Portico"],"relation":{},"ISSN":["0161-3499","1532-950X"],"issn-type":[{"type":"print","value":"0161-3499"},{"type":"electronic","value":"1532-950X"}],"subject":[],"published":{"date-parts":[[2025,9,3]]},"assertion":[{"value":"2025-03-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}