{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:03:05Z","timestamp":1788307385087,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T00:00:00Z","timestamp":1771718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T00:00:00Z","timestamp":1771718400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100011523","name":"College of Veterinary Medicine, University of Minnesota","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011523","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009961","name":"American College of Veterinary Surgeons Foundation","doi-asserted-by":"publisher","award":["6259"],"award-info":[{"award-number":["6259"]}],"id":[{"id":"10.13039\/100009961","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe characteristics of postoperative peritoneal fluid following exploratory laparotomy for naturally\u2010occurring gastrointestinal lesions in horses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Prospective, observational cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>A total of 26 client\u2010owned horses that underwent exploratory laparotomy for naturally\u2010occurring gastrointestinal lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Abdominocentesis was performed pre\u2010 or intraoperatively, and at three time points postoperatively (24, 72, and 168\u2009h). Peritoneal lactate, total protein (TP), total nucleated cell count (TNCC), cytology, and systemic lactate were performed at each time point, if possible. To account for repeated measures, a linear mixed model analysis was performed for each dependent variable listed above.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Horses were divided into groups based on the gastrointestinal lesion diagnosed at surgery (14 strangulating and 12 non\u2010strangulating). Peritoneal lactate (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001) and TP (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.02) were significantly higher preoperatively in horses with strangulating compared to non\u2010strangulating lesions, with no significant differences between lesion groups for any postoperative measurement. Peritoneal lactate and TP concentrations remained above normal for the entire postoperative study period in both groups. Systemic lactate returned to normal concentrations by 24\u2009h postoperatively with both groups being significantly lower than preoperative concentrations (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.02). Peritoneal TNCC concentrations increased in strangulating (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.001) and non\u2010strangulating (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001) horses at 24\u2009h postoperatively compared to preoperatively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Regardless of lesion, peritoneal fluid lactate and TP remained above normal at 1\u2009week following exploratory laparotomy for naturally\u2010occurring gastrointestinal lesions in horses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical significance<\/jats:title>\n                    <jats:p>Current reference values for preoperative fluid sample analyses should not be used in the postoperative period.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vsu.70089","type":"journal-article","created":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T05:31:01Z","timestamp":1771824661000},"page":"568-579","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Serial postoperative peritoneal fluid analyses in horses with naturally\u2010occurring strangulating and non\u2010strangulating gastrointestinal lesions"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9169-6565","authenticated-orcid":false,"given":"Maria E.","family":"Granello","sequence":"first","affiliation":[{"name":"Department of Veterinary Population Medicine, College of Veterinary Medicine University of Minnesota  Saint Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5419-9938","authenticated-orcid":false,"given":"Jenna M.","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Veterinary Population Medicine, College of Veterinary Medicine University of Minnesota  Saint Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana B.","family":"Cleff","sequence":"additional","affiliation":[{"name":"Department of Veterinary Population Medicine, College of Veterinary Medicine University of Minnesota  Saint Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma B. 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