{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T14:19:56Z","timestamp":1783952396122,"version":"3.55.0"},"reference-count":42,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T00:00:00Z","timestamp":1776038400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T00:00:00Z","timestamp":1776038400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate short\u2010 and long\u2010term outcomes and health\u2010related quality of life (Hr\u2010QoL) in dogs with congenital intrahepatic portosystemic shunts (cIHPSS) treated using percutaneous transcatheter embolization (PTCE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Single center retrospective and prospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Sixty\u2010one client\u2010owned dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Medical records were reviewed, and owners completed validated Hr\u2010QoL and congenital portosystemic shunt scoring (Hr\u2010CPSS) questionnaires. Hr\u2010QoL scores ranged from 0 (worst) to 100 (best), and Hr\u2010CPSS from 0 (best) to 100 (worst). Survival was assessed using Kaplan\u2013Meier analysis. Medical or dietary management at final follow\u2010up were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Median follow\u2010up time was 769\u2009days (interquartile range [IQR]: 297\u20131865). Median survival time was 1496\u2009days. At last follow\u2010up, 33 of 59 dogs remained on medical management and\/or a specialized diet. Median Hr\u2010CPSS significantly decreased from prediagnosis (25 [IQR: 18\u201351.3]) to post\u2010PTCE (5 [IQR: 3\u201311];\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001), but not between post\u2010medical and post\u2010PTCE (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.68). Median Hr\u2010QoL scores improved post\u2010PTCE (100 [IQR: 80\u2013100]) compared to prediagnosis (35 [IQR: 10\u201350],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.0001), and post\u2010medical (75 [IQR: 40\u201390],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.005) as well as between prediagnosis and post\u2010medical (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.038). One\u2010, two\u2010, and five\u2010year survival rates were 83%, 66%, and 54%, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Treatment of cIHPSS with PTCE in dogs was associated with a good long\u2010term survival and significant improvement in QoL and clinical signs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Impact<\/jats:title>\n                    <jats:p>The combination of PTCE and targeted medical management provides an effective minimally invasive treatment option for dogs with cIHPSS, supporting improved longevity and quality of life.<\/jats:p>\n                  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