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A prospective noninferiority trial was designed in order to assess skin quality and scar formation by use of subjective (<jats:styled-content style=\"fixed-case\">V<\/jats:styled-content>ancouver <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>car <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cale; <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>atient and <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>bserver <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>car <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ssessment <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cale) and objective (noninvasive cutometry) burn scar assessment tools. All items of the <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>atient and <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>bserver <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>car <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ssessment <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cale, except vascularity, were found to be noninferior in the areas covered with the temporary skin substitute vs. autologous skin. Results of objective scar evaluation showed comparable viscoelastic parameters without reaching noninferiority. Overall, the outcome of deep dermal burns covered with a polylactide\u2010based temporary skin substitute revealed satisfactory results in terms of scar formation and skin quality as compared with autologous skin. This paper supports its use in deep dermal burns, where autologous skin donor sites require either to be reserved for coverage of full\u2010thickness skin defects in severe burns or to be saved for reduction of additional morbidity in selected patient collectives.<\/jats:p>","DOI":"10.1111\/wrr.12050","type":"journal-article","created":{"date-parts":[[2013,4,29]],"date-time":"2013-04-29T15:44:48Z","timestamp":1367250288000},"page":"402-409","source":"Crossref","is-referenced-by-count":12,"title":["The use of a polylactide\u2010based copolymer as a temporary skin substitute in deep dermal burns: 1\u2010year follow\u2010up results of a prospective clinical noninferiority trial"],"prefix":"10.1111","volume":"21","author":[{"given":"Harald F.","family":"Selig","sequence":"first","affiliation":[{"name":"Vienna Burn Center Division of Plastic and Reconstructive Surgery Department of Surgery Medical University of Vienna  Vienna Austria"},{"name":"Division of Plastic, Aesthetic and Reconstructive Surgery Department of Surgery Medical University Graz  Graz Austria"},{"name":"Department of Hand, Plastic and Reconstructive Surgery with Burn Unit Eberhard\u2010Karls\u2010University of Tuebingen  BG Trauma Center Tuebingen Tuebingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maike","family":"Keck","sequence":"additional","affiliation":[{"name":"Vienna Burn Center Division of Plastic and Reconstructive Surgery Department of Surgery Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David B.","family":"Lumenta","sequence":"additional","affiliation":[{"name":"Division of Plastic, Aesthetic and Reconstructive Surgery Department of Surgery Medical University Graz  Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Mittlb\u00f6ck","sequence":"additional","affiliation":[{"name":"Informatics and Intelligent Systems Section for Clinical Biometrics Medical University Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars P.","family":"Kamolz","sequence":"additional","affiliation":[{"name":"Division of Plastic, Aesthetic and Reconstructive Surgery Department of Surgery Medical University Graz  Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,4,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2009.08.016"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10353-008-0380-6"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1252044"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2009.05.010"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0305-4179(94)90088-4"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/BCR.0b013e318198a2d6"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.5301\/IJAO.2011.6400"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199803000-00004"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-5182(97)80033-9"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2006.04.024"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-965234"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e318056bbf6"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2006.10.393"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2011.07.010"},{"key":"e_1_2_7_16_1","unstructured":"MerzKM SieversR ReichertB.Suprathel\u00ae for coverage of superficial dermal burns of the face.2011. doi:10.3205\/vmed000008. 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