{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:21:31Z","timestamp":1790619691571,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,6,17]],"date-time":"2015-06-17T00:00:00Z","timestamp":1434499200000},"content-version":"vor","delay-in-days":108,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000056","name":"National Institute of Nursing Research","doi-asserted-by":"publisher","award":["7R01NR013888"],"award-info":[{"award-number":["7R01NR013888"]}],"id":[{"id":"10.13039\/100000056","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wound Repair Regeneration"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The Agency for Healthcare Research and Quality patient safety indicators (PSI) were developed as a metric of hospital complication rates. PSI\u201014 measures postoperative wound dehiscence and specifically how often a surgical wound in the abdominal or pelvic area fails to heal after abdominopelvic surgery. Wound dehiscence is estimated to occur in 0.5\u20133.4% of abdominopelvic surgeries, and carries a mortality of up to 40%. Postoperative wound dehiscence has been adopted as a surrogate safety outcome measure as it impacts morbidity, length of stay, healthcare costs and readmission rates. Postoperative wound dehiscence cases from the Nationwide Inpatient Sample demonstrate 9.6% excess mortality, 9.4 days of excess hospitalization and $40,323 in excess hospital charges relative to matched controls. The purpose of the current study was to investigate the associations between PSI\u201014 and measurable medical and surgical comorbidities using the Explorys technology platform to query electronic health record data from a large hospital system serving a diverse patient population in the Washington, DC and Baltimore, MD metropolitan areas. The study population included 25,636 eligible patients who had undergone abdominopelvic surgery between January 1, 2008 and December 31, 2012. Of these cases, 786 (2.97%) had postoperative wound dehiscence. Patient\u2010associated comorbidities were strongly associated with PSI\u201014, suggesting that this indicator may not solely be an indicator of hospital safety. There was a strong association between PSI\u201014 and opioid use after surgery and this finding merits further investigation.<\/jats:p>","DOI":"10.1111\/wrr.12268","type":"journal-article","created":{"date-parts":[[2015,2,14]],"date-time":"2015-02-14T00:00:54Z","timestamp":1423872054000},"page":"184-190","source":"Crossref","is-referenced-by-count":74,"title":["Postoperative wound dehiscence: Predictors and associations"],"prefix":"10.1111","volume":"23","author":[{"given":"Victoria K.","family":"Shanmugam","sequence":"first","affiliation":[{"name":"Division of Rheumatology, Wound Healing and Limb Preservation Center, Ideas to Health Laboratory The George Washington University, School of Medicine and Health Sciences Washington DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Bioinformatics MedStar Health Research Institute, Georgetown\u2010Howard Universities Center for Clinical and Translational Science Hyattsville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen Kim","family":"Evans","sequence":"additional","affiliation":[{"name":"Center for Wound Healing MedStar Georgetown University Hospital Washington DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"McNish","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Wound Healing and Limb Preservation Center, Ideas to Health Laboratory The George Washington University, School of Medicine and Health Sciences Washington DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anirban N.","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Wound Healing and Limb Preservation Center, Ideas to Health Laboratory The George Washington University, School of Medicine and Health Sciences Washington DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara S.","family":"Couch","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Wound Healing and Limb Preservation Center, Ideas to Health Laboratory The George Washington University, School of Medicine and Health Sciences Washington DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihriye","family":"Mete","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Bioinformatics MedStar Health Research Institute, Georgetown\u2010Howard Universities Center for Clinical and Translational Science Hyattsville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nawar","family":"Shara","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Bioinformatics MedStar Health Research Institute, Georgetown\u2010Howard Universities Center for Clinical and Translational Science Hyattsville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,6,17]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"http:\/\/www.qualityindicators.ahrq.gov\/Downloads\/Modules\/PSI\/V42\/Composite_User_Technical_Specification_PSI.pdf"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/110241501750215221"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-4804(02)00097-5"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(05)70571-5"},{"key":"e_1_2_7_6_1","unstructured":"National Quality Measures C. Postoperative wound dehiscence (provider\u2010level): rate of reclosure of postoperative disruption of abdominal wall per 1 000 cases of abdominopelvic surgery.http:\/\/www.qualitymeasures.ahrq.gov\/content.aspx?id=38524&search=psi+14"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0b013e318270c0f7"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-009-0277-y"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1062860612459070"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2718-3"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/amiajnl-2011-000782"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-014-1423-2"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2013.10.009"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2011.01.053"},{"key":"e_1_2_7_15_1","article-title":"Identity crisis: An examination of the costs and benefits of a unique patient identifier for the U.S. health care system","author":"Hillestad R","year":"2008","journal-title":"RAND Corporation Monograph"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-011-1710-9"},{"key":"e_1_2_7_17_1","first-page":"747946","article-title":"Lower extremity ulcers in systemic sclerosis: Features and response to therapy","author":"Shanmugam V","year":"2010","journal-title":"Int J Rheumatol"},{"key":"e_1_2_7_18_1","first-page":"534","article-title":"Lower extremity ulcers in connective tissue disease","volume":"10","author":"Shanmugam V","year":"2008","journal-title":"Isr Med Assoc J"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2011.00899.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1999.tb08692.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2000.00801.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.shk.0000126904.67614.21"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellimm.2010.08.002"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.090457"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2009.03.003"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2012.71"}],"container-title":["Wound Repair and Regeneration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fwrr.12268","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/wrr.12268","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T19:58:10Z","timestamp":1696190290000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/wrr.12268"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1111\/wrr.12268"],"URL":"https:\/\/doi.org\/10.1111\/wrr.12268","archive":["Portico"],"relation":{},"ISSN":["1067-1927","1524-475X"],"issn-type":[{"value":"1067-1927","type":"print"},{"value":"1524-475X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3]]}}}