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Despite the application of many diverse techniques, pressure ulcers remain exceptionally difficult to heal because many ulcer elimination techniques have minimal effects, and although other techniques may appear to be effective, the evidence supporting their efficacy is weak. However, increasing evidence indicates that other techniques, such as the application of platelet\u2010rich plasma, vacuum assisted closure, electrical stimulation, and hyperbaric oxygen therapy are effective and should be substituted for the older techniques. This review describes different standard and novel techniques that have been tested for eliminating pressure ulcers and discusses the relative efficacy of these techniques.<\/jats:p>","DOI":"10.1111\/wrr.12284","type":"journal-article","created":{"date-parts":[[2015,3,20]],"date-time":"2015-03-20T15:55:23Z","timestamp":1426866923000},"page":"312-317","source":"Crossref","is-referenced-by-count":16,"title":["Improving the ability to eliminate wounds and pressure ulcers"],"prefix":"10.1111","volume":"23","author":[{"given":"Damien P.","family":"Kuffler","sequence":"first","affiliation":[{"name":"Institute of Neurobiology University of Puerto Rico San Juan Puerto Rico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,7,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1093\/ajhp\/61.18.1895","article-title":"Management of pressure ulcers","volume":"61","author":"Cannon 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