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PG is increasingly used for the treatment of a variety of soft and hard tissue defects, most notably in the management of chronic non\u2010healing wounds. During wound healing, platelets not only play a critical role in primary hemostasis and thrombosis, but also release growth factors and cytokines to promote tissue regeneration, enhance collagen synthesis, and trigger an immune response. This review addresses a variety of aspects relevant to the functions of well\u2010known platelet growth factors, animal and clinical studies of PG in the last decade, and different sources of platelets for PG. PG is used for non\u2010healing chronic wounds, such as oral ulcerations related to epidermolysis bullosa and chronic graft\u2010versus\u2010host disease, for those, the traditional treatment effect is poor. PG maybe provide a new therapeutic direction for these diseases. Nevertheless, some uncertainty is present, the number of clinical studies is not enough. Hence, randomized controlled trials are still required to study the potential of the use of PG in the near future.<\/jats:p>","DOI":"10.1111\/wrr.12896","type":"journal-article","created":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T10:05:06Z","timestamp":1616407506000},"page":"370-379","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Current applications of platelet gels in wound healing\u2014A review"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9718-101X","authenticated-orcid":false,"given":"Shujun","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Hematology and Oncology, Zhongda Hospital, School of Medicine Southeast University Nanjing China"},{"name":"School of Medicine Southeast University Nanjing China"},{"name":"Jinling Hospital Department Blood Transfusion Nanjing University, School Medicine Nanjing 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