{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T08:37:46Z","timestamp":1791362266322,"version":"4.3.1"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T00:00:00Z","timestamp":1700611200000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Wound Repair Regeneration"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The current study aimed to evaluate the dispersal of solution and microbes (aerosol) in the clinical environment during treatment with Low\u2010frequency contact ultrasonic debridement (LFCUD) with or without suction attachment in patients with diabetic foot ulcers (DFUs). We performed 20 treatments in 10 patients divided into two groups to receive the proposed LFCUD modalities. We measured the microbial load of the environment pre\u2010treatment (sample M1), during treatment with each LFCUD modality (sample M2) and post\u2010treatment (sample M3). The use of LFCUD debridement without a suction attachment results in significantly higher immediate contamination of the clinic environment than the suction attachment, particularly during the procedure (1.70\u2009\u00b1\u20090.98 log 10\u2009CFU\/mL versus 0.77\u2009\u00b1\u20090.85 log 10\u2009CFU\/mL, <jats:italic>p<\/jats:italic>\u2009=\u20090.035). When suction is not applied, there are statistically significant differences depending on whether the DFUs are neuropathic or neuroischemic, finding a greater number of microorganisms with high loads in neuropathic DFUs. We found a statistically significant positive correlation between wound area (<jats:italic>r<\/jats:italic>\u2009=\u20090.450, <jats:italic>p<\/jats:italic>\u2009=\u20090.047) and TBI (<jats:italic>r<\/jats:italic>\u2009=\u20090.651, <jats:italic>p<\/jats:italic>\u2009=\u20090.006) with the bacterial load during the LFCUD. Based on our results, we recommend using the personal protective equipment required to protect staff members and patients during treatment with LFCUD and using a suction attachment where clinically possible to reduce clinic environmental pollution, especially in neuropathic DFUs and those with larger areas.<\/jats:p>","DOI":"10.1111\/wrr.13124","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T15:23:37Z","timestamp":1699889017000},"page":"745-751","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A deeper look at low\u2010frequency contact ultrasonic debridement in the clinical management of patients with diabetic foot ulcers"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4674-3822","authenticated-orcid":false,"given":"Francisco J.","family":"\u00c1lvaro\u2010Afonso","sequence":"first","affiliation":[{"name":"Complutense University of Madrid University Podiatric Clinic, Instituto de Investigaci\u00f3n Sanitaria del Hospital Cl\u00ednico San Carlos (IdISSC)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8545-0611","authenticated-orcid":false,"given":"Sebasti\u00e1n","family":"Flores\u2010Escobar","sequence":"additional","affiliation":[{"name":"Complutense University of Madrid University Podiatric Clinic, Instituto de Investigaci\u00f3n Sanitaria del Hospital Cl\u00ednico San Carlos (IdISSC)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Sevillano\u2010Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Microbiology Section Medical Faculty of Complutense University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1424-5087","authenticated-orcid":false,"given":"Yolanda","family":"Garc\u00eda\u2010\u00c1lvarez","sequence":"additional","affiliation":[{"name":"Complutense University of Madrid University Podiatric Clinic, Instituto de Investigaci\u00f3n Sanitaria del Hospital Cl\u00ednico San Carlos (IdISSC)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Garc\u00eda\u2010Madrid","sequence":"additional","affiliation":[{"name":"Complutense University of Madrid University Podiatric Clinic, Instituto de Investigaci\u00f3n Sanitaria del Hospital Cl\u00ednico San Carlos (IdISSC)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 L.","family":"L\u00e1zaro\u2010Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Complutense University of Madrid University Podiatric Clinic, Instituto de Investigaci\u00f3n 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