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An illustrative case was also reported. The review used the PRISMA checklist and was registered in PROSPERO. The entire literature period up to April 2023 was searched in the EMBASE\/Elsevier, Cochrane, Scopus, Medline, BVS, SciELO, and Lilacs databases. The inclusion criteria embraced primary studies, clinical trials, prospective or retrospective cohorts, case series, case\u2013control studies and case reports. Three hundred and sixty\u2010one studies were found and 12 of them were included, consisting of 9 case reports and 3 case series. The most common triggering factor for keloid formation was circumcision, in 11 of the cases, of which more than half occurred in prepubescent children. Several therapies, associated or isolated, were used to treat the cases. Only one of the reported patients had scar recurrence after surgical treatment. Studies with better scientific evidence are needed to understand the involvement of keloids in male genitalia. However, keloid formation in this topography is rare, making it difficult to carry out more elaborate studies.<\/jats:p>","DOI":"10.1111\/wrr.13157","type":"journal-article","created":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T04:54:21Z","timestamp":1707886461000},"page":"171-181","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Keloids in male genitalia\u2014Systematic review and illustrative case report"],"prefix":"10.1111","volume":"32","author":[{"given":"Felipe Contoli","family":"Isoldi","sequence":"first","affiliation":[{"name":"Postgraduate Program in Translational Surgery at Universidade Federal de S\u00e3o Paulo \u2013 Escola Paulista de Medicina (Unifesp\/EPM)  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariane","family":"Garcia","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Translational Surgery at Universidade Federal de 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