{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T22:03:01Z","timestamp":1783807381203,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T00:00:00Z","timestamp":1776297600000},"content-version":"vor","delay-in-days":46,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Wound Repair Regeneration"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Negative pressure wound therapy relies on suction, commonly set to \u2212125\u2009mmHg, to evacuate wound fluid, but dysvascular and pressure injuries often respond unpredictably. Newton's third law indicates that negative pressure applies an equal and opposite contact pressure on the wound surface, and this study quantified this contact pressure across dressing types, wound configurations and suction levels. Using a porcine explant model, central and peripheral contact pressure measurements were obtained beneath black reticulated open cell foam, white foam and a novel thermoplastic elastomer dressing across plexiglass, intact skin, shallow and deep wounds under \u221250, \u221275 and \u2212125\u2009mmHg. Contact pressure increased proportionally with negative pressure, and multivariable modelling demonstrated that dressing type, wound type and suction level significantly influenced pressure, with negative pressure explaining most of the variance (0.77 and 0.68). Thermoplastic elastomer at \u221250\u2009mmHg in deep wounds produced the lowest contact pressure, whereas black reticulated open cell foam and white foam at \u2212125\u2009mmHg generated elevated contact pressures of approximately +125 to +195\u2009mmHg. These findings show that black reticulated open cell foam at conventional \u2212125\u2009mmHg can create hypoperfusion conditions, whereas thermoplastic elastomer consistently produces the lowest pressures and may enhance perfusion at lower suction levels, offering a physiologic explanation for improved clinical outcomes in dysvascular and pressure injuries treated with reduced negative pressure.<\/jats:p>","DOI":"10.1111\/wrr.70157","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T04:36:28Z","timestamp":1776400588000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Contact Pressure Under Traditional Foam and Novel Thermoplastic Elastomer Negative Pressure Wound Therapy Interfaces"],"prefix":"10.1111","volume":"34","author":[{"given":"Michael S.","family":"Shuler","sequence":"first","affiliation":[{"name":"Athens Orthopedic Clinic  Athens Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colton C.","family":"Mowers","sequence":"additional","affiliation":[{"name":"Rush University Medical Center  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meera M.","family":"Dhodapkar","sequence":"additional","affiliation":[{"name":"Mayo Clinic Department of Orthopedic Surgery  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell","family":"Greenberg","sequence":"additional","affiliation":[{"name":"The Geneva Foundation  Tacoma Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Ngendahimana","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Rainbow Babies and Children's Hospital  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett A.","family":"Freedman","sequence":"additional","affiliation":[{"name":"Mayo Clinic Department of Orthopedic Surgery  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2011.06.023"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2021.02.001"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12111"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181fed52a"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2011.00741.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12658"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e318196b97b"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtv.2019.09.001"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtv.2019.12.004"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12190"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000006652"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31818237ac"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000007450"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.3"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.70144"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.13084"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000438046.83515.6a"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.2947358"},{"key":"e_1_2_9_20_1","unstructured":"M. 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