{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T23:18:10Z","timestamp":1790291890125,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T00:00:00Z","timestamp":1722384000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T00:00:00Z","timestamp":1722384000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["sigmapubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Worldviews Ev Based Nurs"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Delirium is a common complication among adults. It is essential to improve the outcomes of delirium.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To systematically synthesize the evidence on the effectiveness of the nurse\u2010led non\u2010pharmacological interventions on outcomes of delirium in adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Electronic databases including CINAHL, Cochrane Library, MEDLINE, EMBASE, PubMed, Web of Science, PsycINFO, and Clinical Trial Registration were searched comprehensively by the authors. The authors reviewed the full text and assessed the risk of bias using the Cochrane Risk of Bias Tool 2.0. The meta\u2010analysis was performed using RevMan and Stata software. The forest plots showed the overall effect of the included study and the\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      test was used to assess the degree of heterogeneity between studies. Random effects models were used to analyze studies with significant heterogeneity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 32 studies (10,122 participants) were included in the meta\u2010analysis. Nurse\u2010led non\u2010pharmacological interventions resulted in a significantly lower incidence of delirium compared with the usual care\/control group (risk ratio\u2009=\u20090.74,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001) and reduced mortality in the hospital compared with usual care (risk ratio\u2009=\u20090.81,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.04). However, the implementation of nurse\u2010led, non\u2010pharmacological interventions had no significant effect on the duration, severity of delirium, or length of hospital stay.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Linking Evidence to Action<\/jats:title>\n                    <jats:p>Our findings suggest that the nurse\u2010led, non\u2010pharmacological strategy was effective in reducing the incidence of delirium and mortality in the hospital. Multicomponent interventions were the most effective strategy for reducing the incidence of delirium in adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/wvn.12739","type":"journal-article","created":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:40:36Z","timestamp":1722472836000},"page":"514-527","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Effectiveness of nurse\u2010led non\u2010pharmacological interventions on outcomes of delirium in adults: A meta\u2010analysis of randomized controlled trials"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0228-1849","authenticated-orcid":false,"given":"Jiamin","family":"Wang","sequence":"first","affiliation":[{"name":"School of Nursing Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yating","family":"Lu","sequence":"additional","affiliation":[{"name":"School of Nursing Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Nursing Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8633-5404","authenticated-orcid":false,"given":"Ying","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Nursing Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2016.02.002"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16695"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aucc.2022.08.005"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD013307.pub2"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2022.05.058"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2022.104239"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.4037\/ajcc2015658"},{"issue":"7","key":"e_1_2_9_9_1","first-page":"753","article-title":"Systematic detection and multidisciplinary care of delirium in older medical inpatients: A randomized trial","volume":"167","author":"Cole M. 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