{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:32:47Z","timestamp":1792607567207,"version":"4.5.0"},"reference-count":67,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["sigmapubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Worldviews Ev Based Nurs"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cancer survivors often receive inadequate pain management, leading to impaired quality of life. Despite their importance, evidence on the global prevalence of chronic pain in cancer survivors remains insufficiently clear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The systematic review and proportional meta\u2010analysis aimed to estimate the pooled global prevalence of chronic pain among cancer survivors and to explore heterogeneity stratified by geographic region, cancer type, pain duration, and pain assessment tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Five databases (PubMed, Embase, Cochrane Library, CINAHL, and China National Knowledge Infrastructure) were searched up to September 2024 for studies in English or Chinese. The review followed MOOSE and PRISMA guidelines with PROSPERO registration (CRDxx). Studies were included if they reported chronic pain prevalence in cancer survivors using validated instruments or solely reported chronic pain. Two reviewers independently screened studies, extracted data, and assessed quality using the JBI Critical Appraisal Checklist for Analytical Cross\u2010Sectional Studies. Pooled prevalence and 95% prediction intervals were calculated using a random\u2010effects model with Freeman\u2013Tukey double arcsine transformation. Subgroup analysis was used to explore heterogeneity. Leave\u2010one\u2010out analysis explored robustness. Funnel plot and Egger's test were used to examine publication bias.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 36 studies involving 39,806 participants were included. The pooled prevalence of chronic pain among cancer survivors was 41% (95% CI: 34%\u201349%) after testing robustness, with significant heterogeneity (\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>\n                        <jats:italic>2<\/jats:italic>\n                      <\/jats:sup>\n                      \u2009=\u200999.32%). Subgroup analysis indicated significant group differences in prevalence rates by geographic region, cancer type, and pain duration (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Linking Evidence to Action<\/jats:title>\n                    <jats:p>These findings stress the need for more extensive and tailored chronic pain management in current clinical practice. Additional research on chronic pain outcomes among pediatric cancer survivors, cancer populations within Africa and South America, and those with cancer types other than breast cancer is needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trail Registration<\/jats:title>\n                    <jats:p>PROSPERO Registration: CRD42024597090.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/wvn.70122","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T06:28:01Z","timestamp":1770186481000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Global Prevalence of Chronic Pain Among Cancer Survivors: A Systematic Review and Proportional Meta\u2010Analysis of Observational Studies"],"prefix":"10.1111","volume":"23","author":[{"given":"Pak Kit","family":"Wong","sequence":"first","affiliation":[{"name":"School of Nursing, LKS Faculty of Medicine The University of Hong Kong  Pokfulam Hong Kong SAR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5424-3705","authenticated-orcid":false,"given":"Lizhen","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Nursing, LKS Faculty of Medicine The University of Hong Kong  Pokfulam Hong Kong SAR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9443-4082","authenticated-orcid":false,"given":"Mu\u2010Hsing","family":"Ho","sequence":"additional","affiliation":[{"name":"School of Nursing, LKS Faculty of Medicine The University of Hong Kong  Pokfulam Hong Kong SAR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9551-0991","authenticated-orcid":false,"given":"Chia\u2010Chin","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Nursing, LKS Faculty of Medicine The University of Hong Kong  Pokfulam Hong Kong SAR"},{"name":"Alice Ho Miu Ling Nethersole Charity Foundation Professor in Nursing  Tai Po Hong Kong SAR"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10147\u2010012\u20100377\u20109"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(17)33326\u20103"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/life15020177"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2012.692884"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010018\u20104670\u20109"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001363"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1515\/sjpain\u20102023\u20100074"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9829"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764\u2010019\u201000843\u20100"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6736a2"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/life12091328"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PPO.0000000000000399"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.26635\/6965.6524"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.2067"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764\u2010021\u201001010\u20100"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/ajp.0000000000000377"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2021.09.011"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdy152"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000237"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010017\u20104485\u20100"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010023\u201007846\u20109"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e31822a6887"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2019.10.027"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2019.1439"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12262\u2010017\u20101663\u20106"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13701"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010023\u201007678\u20107"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2012.07.023"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/13557858.2016.1246428"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/pm\/pnaa414"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/pme.12223"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13187\u2010019\u201001548\u20109"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12282\u2010019\u201000979\u2010y"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2024.3233"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f1865"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol30070500"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1200\/GO.20.00180"},{"key":"e_1_2_10_40_1","volume-title":"JBI Manual for Evidence Synthesis","author":"Moola S.","year":"2020"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1177\/10499091231164634"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2021.03.001"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.31557\/APJCP.2022.23.6.1945"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1177\/10499091221143098"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2022.106937"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/papr.13098"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1097\/NJH.0000000000000507"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2019.2971"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2013.12.239"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296\u2010011\u20102104\u20107"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12905\u2010023\u201002766\u20106"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15030591"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136\u2010017\u20101544\u20102"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4218"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2015.07.010"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.15.2008"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2019.0038"},{"issue":"1","key":"e_1_2_10_58_1","first-page":"52","article-title":"Chronic Pain and Other Symptoms Following Treatment of Breast Cancer","volume":"114","author":"Tasmuth T.","year":"1998","journal-title":"Duodecim"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/jrh.12835"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000160"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2016.02.010"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010021\u201006332\u20104"},{"key":"e_1_2_10_63_1","volume-title":"WHO Guidelines for the Pharmacological and Radiotherapeutic Management of Cancer Pain in Adults and Adolescents","author":"World Health Organization","year":"2018"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000002291"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889\u2010025\u201021406\u20102"},{"issue":"254","key":"e_1_2_10_66_1","first-page":"10","article-title":"Epidemiology of Neuropathic Chronic Pain in Oncology Patients","volume":"5","author":"Zhumaliyeva V.","year":"2016","journal-title":"Georgian Medical News"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000002557"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2024.104612"}],"container-title":["Worldviews on Evidence-Based Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/wvn.70122","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/wvn.70122","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/wvn.70122","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T03:24:01Z","timestamp":1777605841000},"score":1,"resource":{"primary":{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/10.1111\/wvn.70122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":67,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1111\/wvn.70122"],"URL":"https:\/\/doi.org\/10.1111\/wvn.70122","archive":["Portico"],"relation":{},"ISSN":["1545-102X","1741-6787"],"issn-type":[{"value":"1545-102X","type":"print"},{"value":"1741-6787","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"2025-07-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70122"}}