{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T03:13:22Z","timestamp":1777864402491,"version":"3.51.4"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T00:00:00Z","timestamp":1776556800000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["sigmapubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Worldviews Ev Based Nurs"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Parenting concerns, stemming from cancer's projected impact on children, are a common and significant source of emotional distress for parents. A quantitative synthesis of existing data is critically absent, and the role of modulating factors (e.g., male sex, single parenthood, and the number of children) remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This meta\u2010analysis aims to quantify the association between parenting concerns and emotional distress in cancer patients, examining male sex, single parenthood, and number of children as key moderators.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This systematic review and meta\u2010analysis followed PRISMA guidelines. Searches (PubMed, Embase, PsycINFO, Airiti Library; inception\u2010November 2025) identified observational studies of adult cancer patients with minor children. Data on parenting concerns, anxiety, and depression were extracted and appraised using a modified JBI Checklist. Correlations were synthesized. Meta\u2010regression addressed the quantitative void, examining male sex, single parenthood, and number of children as key moderators. Publication bias and sensitivity were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We included 12 studies (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u20093895). Our meta\u2010analysis found significant positive associations (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.50,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) between parenting concerns and both anxiety and depression. Meta\u2010regression, controlling for time since diagnosis, identified male sex, single parenthood, and fewer children as significant moderators for anxiety (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with similar trends for depression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Linking Evidence to Action<\/jats:title>\n                    <jats:p>This meta\u2010analysis highlights parenting concerns linked to distress in cancer patients, with fathers, single parents, and those with fewer children particularly vulnerable. Routine assessment and tailored, family\u2010centered psychosocial interventions are urgently needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:styled-content style=\"fixed-case\">PROSPERO<\/jats:styled-content>\n                      Registration\n                    <\/jats:title>\n                    <jats:p>This systematic review was registered with the International Prospective Register of Systematic Reviews and Meta\u2010analysis (PROSPERO; Registration No. CRD42024592899).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/wvn.70127","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T02:25:05Z","timestamp":1776651905000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Parenting Concerns and Emotional Distress in Cancer Patients With Minor Children: A Meta\u2010Analysis of Key Moderators"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1381-2652","authenticated-orcid":false,"given":"Yuan\u2010Ju","family":"Liao","sequence":"first","affiliation":[{"name":"Department of Long\u2010Term Care College of Nursing, Asia University  Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5771-5080","authenticated-orcid":false,"given":"Ya\u2010Chuan","family":"Tseng","sequence":"additional","affiliation":[{"name":"Department of Nursing Chang Gung University of Science and Technology  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7006-9164","authenticated-orcid":false,"given":"Hsin\u2010Yi","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Nursing, College of Medicine National Taiwan University  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7200-7373","authenticated-orcid":false,"given":"Yun\u2010Hsiang","family":"Lee","sequence":"additional","affiliation":[{"name":"School of Nursing, College of Medicine National Taiwan University  Taipei Taiwan"},{"name":"Department of Nursing National Taiwan University Cancer Center  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0313-2634","authenticated-orcid":false,"given":"Yeur\u2010Hur","family":"Lai","sequence":"additional","affiliation":[{"name":"School of Nursing MacKay Medical University  New Taipei City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6278-9962","authenticated-orcid":false,"given":"Yuan\u2010Yuan","family":"Fang","sequence":"additional","affiliation":[{"name":"Second Degree Bachelor of Science in Nursing, College of Medicine National Taiwan University  Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,19]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119558378"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0066844"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3070"},{"key":"e_1_2_13_5_1","volume-title":"Global Cancer Observatory: Cancer Today","author":"Ferlay J.","year":"2024"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.6173"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41118\u2010020\u201000111\u20105"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj\u20102023\u2010076625"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010025\u201009225\u2010y"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4049"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2021.765314"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5912"},{"key":"e_1_2_13_13_1","first-page":"33","article-title":"Chinese Version of Parenting Concerns Questionnaire Among Cancer Patients: Translation, Validity and Reliability","volume":"38","author":"Kang T.","year":"2021","journal-title":"Nursing Journal of Chinese People's Liberation Army"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4904"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12144\u2010024\u201006008\u20102"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.70057"},{"issue":"1","key":"e_1_2_13_17_1","first-page":"15","article-title":"The Functioning of Single Women With Breast Cancer and Their School\u2010Aged Children","volume":"4","author":"Lewis F. M.","year":"1996","journal-title":"Cancer Practice"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnsa.2024.100210"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.2340\/1651\u2010226x.2024.40728"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.6310"},{"key":"e_1_2_13_21_1","unstructured":"Moola S. Z.Munn C.Tufanaru et\u00a0al.2017.\u201cSystematic reviews of etiology and risk. Joanna Briggs Institute reviewer's manual.\u201d"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.27572"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.12021"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.12492"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3935"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010018\u20104518\u20101"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2017.09.021"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/10499091211049801"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010022\u201007399\u20103"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21489"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/ncc.0000000000001276"},{"key":"e_1_2_13_33_1","article-title":"Parenting Under Pressure: A Cross\u2010Sectional Questionnaire Study of Psychological Distress, Parenting Concerns, Self\u2010Efficacy, and Emotion Regulation in Parents With Cancer","volume":"63","author":"Strandh M. R.","year":"2024","journal-title":"Acta Oncologica"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.13315"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25368"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyae041"}],"container-title":["Worldviews on Evidence-Based Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/wvn.70127","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/wvn.70127","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/wvn.70127","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:41:23Z","timestamp":1777527683000},"score":1,"resource":{"primary":{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/10.1111\/wvn.70127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1111\/wvn.70127"],"URL":"https:\/\/doi.org\/10.1111\/wvn.70127","archive":["Portico"],"relation":{},"ISSN":["1545-102X","1741-6787"],"issn-type":[{"value":"1545-102X","type":"print"},{"value":"1741-6787","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2025-07-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70127"}}