{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T04:05:54Z","timestamp":1789531554443,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["sigmapubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Worldviews Ev Based Nurs"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To synthesize randomized controlled trials (RCTs) regarding the effectiveness of pre\u2010pregnancy weight loss interventions on the risk of gestational diabetes mellitus (GDM) in women with overweight or obesity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Comprehensive literature searches were conducted across nine databases from inception to May 2024. RCTs comparing pre\u2010pregnancy weight loss interventions with blank control or active control among adult women with overweight or obesity were included. Meta\u2010analyses, using a random\u2010effects model, were performed to pool results of RCTs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Six studies, including 1632 participants, were included. The effectiveness of pre\u2010pregnancy weight loss interventions on changes in weight and body mass index (BMI) was statistically significant (mean difference [MD]\u2009=\u2009\u22126.02, 95% confidence interval [CI] [\u22128.94, \u22123.10],\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200998%; MD\u2009=\u2009\u22122.22, 95% CI [\u22123.44, \u22121.00],\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200998%). However, there was no statistically significant difference in the risk of GDM in women receiving pre\u2010pregnancy weight loss interventions compared with controls (Odd Ratio [OR]\u2009=\u20090.70, 95% CI [0.48, 1.03],\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20092%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Linking Evidence to Action<\/jats:title>\n                    <jats:p>Pre\u2010pregnancy weight loss interventions do not significantly impact the risk of GDM in women with overweight or obesity. Due to the small number of studies, small sample size, and large heterogeneity of pre\u2010pregnancy weight loss interventions, further research is required.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Trial Registration:<\/jats:bold>\n                      ClinicalTrials.gov identifier: CRD42023482808\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/wvn.70128","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T10:31:48Z","timestamp":1779359508000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of Pre\u2010Pregnancy Weight Loss Interventions on the Risk of Gestational Diabetes Mellitus in Overweight or Obese Women: A Systematic Review and Meta\u2010Analysis of Randomized Controlled Trials"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-1842-1299","authenticated-orcid":false,"given":"Yucheng","family":"Jiang","sequence":"first","affiliation":[{"name":"Obstetrics and Gynaecology Hospital of Fudan University  Shanghai China"},{"name":"School of Nursing Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilin","family":"Mao","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology Hospital of Fudan University  Shanghai China"},{"name":"School of Nursing Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology Hospital of Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Wang","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology Hospital of Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of Nursing Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Ding","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology Hospital of Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,21]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Ashra N. B. R.Spong P.Carter et\u00a0al.2015.\u201cA Systematic Review and Meta\u2010Analysis Assessing the Effectiveness of Pragmatic Lifestyle Interventions for the Prevention of Type 2 Diabetes Mellitus in Routine Practice.\u201dPublic Health England. August 26.https:\/\/www.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/456147\/PHE_Evidence_Review_of_diabetes_prevention_programmes\u2010_FINAL.pdf."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.07.015"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42255\u2010023\u201000829\u20104"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cob.12180"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13532"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14061259"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803720"},{"key":"e_1_2_10_9_1","unstructured":"Higgins J. P. T. J.Thomas J.Chandler et\u00a0al.2024.\u201cAssessing Risk of Bias in a Randomized Trial.\u201dThe Cochrane Collaboration. August 22.https:\/\/www.cochrane.org\/authors\/handbooks\u2010and\u2010manuals\/handbook\/current\/chapter\u201008."},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13325"},{"key":"e_1_2_10_11_1","first-page":"241","volume-title":"Weight Gain During Pregnancy: Reexamining the Guidelines","author":"Institute of Medicine and National Research Council Committee to Reexamine IOM Pregnancy Weight Guidelines","year":"2009"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jand.2014.07.005"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2018.09.004"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.07.027"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc18\u20101646"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1505297"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13324"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.6133\/apjcn.202209_31(3).0013"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2023.01.037"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.23200"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.22083"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/cob.12048"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1159\/000439413"},{"key":"e_1_2_10_25_1","volume-title":"Stata Statistical Software (Version 16.0) [Computer Program]","author":"StataCorp LLC","year":"2019"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803175"},{"key":"e_1_2_10_27_1","volume-title":"Review Manager (RevMan) (Version 5.4.1) [Computer Program]","author":"The Cochrane Collaboration","year":"2020"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12974"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/gco.0000000000000901"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.3820"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102288\u201014\u2010135"},{"key":"e_1_2_10_32_1","volume-title":"Obesity and Overweight","author":"World Health Organization","year":"2025"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(03)15268\u20103"}],"container-title":["Worldviews on Evidence-Based Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/wvn.70128","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/wvn.70128","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/wvn.70128","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T03:20:59Z","timestamp":1789528859000},"score":1,"resource":{"primary":{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/10.1111\/wvn.70128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,21]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1111\/wvn.70128"],"URL":"https:\/\/doi.org\/10.1111\/wvn.70128","archive":["Portico"],"relation":{},"ISSN":["1545-102X","1741-6787"],"issn-type":[{"value":"1545-102X","type":"print"},{"value":"1741-6787","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,21]]},"assertion":[{"value":"2025-03-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70128"}}