{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T05:32:03Z","timestamp":1793251923411,"version":"4.5.0"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:00:00Z","timestamp":1791849600000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["sigmapubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Worldviews Ev Based Nurs"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background\/Significance<\/jats:title>\n                    <jats:p>Breast biopsies are essential for cancer diagnoses and are often accompanied by heightened procedural anxiety. While local anesthesia addresses procedural pain, it does not lessen psychological distress. Virtual reality (VR) has been explored as a distraction\u2010based intervention that may reduce procedural anxiety.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study evaluated the effects of standard care plus VR compared to standard care alone on patient anxiety, pain, and satisfaction during ultrasound\u2010guided breast biopsy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A single\u2010site, two\u2010arm randomized controlled trial (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200980) compared standard care to standard care plus the use of VR during the ultrasound\u2010guided breast biopsy procedure. Data were collected between 9\/2024 and 5\/2025. Study participants were randomized 1:1 to receive either standard care (control group) or standard care plus VR use (intervention group). Anxiety and pain were assessed pre\u2010 and post\u2010procedure using 11\u2010point numeric rating scales; satisfaction was measured post\u2010procedure. Open\u2010ended responses from the intervention group were analyzed thematically.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results and Findings<\/jats:title>\n                    <jats:p>\n                      Study participants in the intervention group demonstrated significantly greater anxiety reduction compared to the control group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Pain scores did not differ significantly between groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.37). Satisfaction was uniformly high in both groups. Thematic analysis of open\u2010ended responses from the intervention group identified themes related to anxiety reduction, distraction, and perceptions of VR use during the breast biopsy procedure.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/wvn.70183","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T13:11:01Z","timestamp":1791897061000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Use of Virtual Reality to Reduce Procedural Anxiety During Breast Biopsy: A Randomized Controlled Trial"],"prefix":"10.1111","volume":"23","author":[{"given":"Renee","family":"Trambert","sequence":"first","affiliation":[{"name":"Carol W. and Julius A. Rippel Breast Center Morristown Medical Center  Morristown New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Friedman","sequence":"additional","affiliation":[{"name":"Carol W. and Julius A. Rippel Breast Center Morristown Medical Center  Morristown New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveed","family":"Jan","sequence":"additional","affiliation":[{"name":"Carol W. and Julius A. Rippel Breast Center Morristown Medical Center  Morristown New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen","family":"Smorra","sequence":"additional","affiliation":[{"name":"Carol W. and Julius A. Rippel Breast Center Morristown Medical Center  Morristown New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Caruso","sequence":"additional","affiliation":[{"name":"Carol W. and Julius A. Rippel Breast Center Morristown Medical Center  Morristown New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Ribaudo","sequence":"additional","affiliation":[{"name":"Carol W. and Julius A. Rippel Breast Center Morristown Medical Center  Morristown New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0079-9102","authenticated-orcid":false,"given":"Mildred Ortu","family":"Kowalski","sequence":"additional","affiliation":[{"name":"Center for Nursing Innovation and Research Morristown Medical Center  Morristown New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth","family":"Jameson","sequence":"additional","affiliation":[{"name":"Center for Nursing Innovation and Research Morristown Medical Center  Morristown New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8053-5544","authenticated-orcid":false,"given":"Lise","family":"Cooper","sequence":"additional","affiliation":[{"name":"Center for Nursing Innovation and Research Morristown Medical Center  Morristown New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1460-2946","authenticated-orcid":false,"given":"John","family":"Rutledge","sequence":"additional","affiliation":[{"name":"Atlantic Health Clinical Research and Innovation Institute  Morristown New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,13]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlpt.2023.100741"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.32332\/jhsm.1035199"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000003086"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1191\/1478088706qp063oa"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/2473974X20975020"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2020.08.016"},{"key":"e_1_2_14_8_1","first-page":"391","volume-title":"Advances in Pain Research and Therapy: Vol. 12. Issues in Pain Measurement","author":"Cleeland C. S.","year":"1989"},{"key":"e_1_2_14_9_1","volume-title":"Statistical Power Analysis for the Behavioral Sciences","author":"Cohen J.","year":"1988"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10153248"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12904\u2010025\u201001814\u20102"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.17175"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jan.15743"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jopan.2021.09.006"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/frvir.2022.837616"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002508-200009000-00010"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jopan.2021.04.007"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43044\u2010021\u201000224\u2010y"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2022.0319"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423\u2010023\u201003046\u20105"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmn.2023.04.014"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43058\u2010023\u201000442\u20102"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsg.2023.01.014"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/pm\/pnab110"},{"key":"e_1_2_14_25_1","unstructured":"Ozential Digital Therapeutics. n.d.\u201cInformation.\u201dhttps:\/\/ohsnj.com\/."},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.2196\/32721"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/jbi\/wbad088"},{"key":"e_1_2_14_28_1","volume-title":"The Roy Adaptation Model","author":"Roy C.","year":"2009"},{"issue":"6","key":"e_1_2_14_29_1","first-page":"593","article-title":"Virtual Reality as a Distraction Intervention for Older Children Receiving Chemotherapy","volume":"26","author":"Schneider S. M.","year":"2000","journal-title":"Pediatric Nursing"},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2023.06.275"},{"key":"e_1_2_14_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12890\u2010023\u201002304\u2010y"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.1188\/25.CJON.65\u201071"},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jopan.2022.07.005"},{"key":"e_1_2_14_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/SGA.0000000000000733"}],"container-title":["Worldviews on Evidence-Based Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/wvn.70183","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/wvn.70183","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/wvn.70183","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T04:41:06Z","timestamp":1793248866000},"score":1,"resource":{"primary":{"URL":"https:\/\/sigmapubs.onlinelibrary.wiley.com\/doi\/10.1111\/wvn.70183"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/wvn.70183"],"URL":"https:\/\/doi.org\/10.1111\/wvn.70183","archive":["Portico"],"relation":{},"ISSN":["1545-102X","1741-6787"],"issn-type":[{"value":"1545-102X","type":"print"},{"value":"1741-6787","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"2025-10-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70183"}}