{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:39:46Z","timestamp":1773283186440,"version":"3.50.1"},"reference-count":43,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,6,17]],"date-time":"2013-06-17T00:00:00Z","timestamp":1371427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2014,5]]},"abstract":"Summary<\/jats:title>Eight coagulase\u2010positive staphylococci from equines with different pathologies obtained between 2005 and 2011 were investigated. Isolates were characterized by different molecular techniques (spa<\/jats:italic>\u2010, agr<\/jats:italic>\u2010, MLST<\/jats:styled-content>), and clonal relatedness of strains was investigated by A<\/jats:styled-content>paI and S<\/jats:styled-content>maI PFGE<\/jats:styled-content>. Anti\u2010microbial resistance and virulence profiles were determined. Six isolates were identified as S<\/jats:styled-content>taphylococcus aureus<\/jats:italic>, and two as S<\/jats:styled-content>taphylococcus pseudintermedius<\/jats:italic>. Of these, four isolates were methicillin\u2010resistant S<\/jats:styled-content>.\u00a0aureus<\/jats:italic> (MRSA<\/jats:styled-content>) ST<\/jats:styled-content>398 and one S<\/jats:styled-content>.\u00a0pseudintermedius<\/jats:italic> was mec<\/jats:italic>A<\/jats:styled-content> positive and typed as ST<\/jats:styled-content>68. One MRSA ST<\/jats:styled-content>398 strain was isolated in 2005 and might be one of the earliest MRSA ST<\/jats:styled-content>398 descriptions in S<\/jats:styled-content>pain. All 5 mec<\/jats:italic>A<\/jats:styled-content>\u2010positive strains were multidrug resistant and were isolated from hospitalized equines. Three MRSA ST<\/jats:styled-content>398 strains carried the recently described transposon Tn559<\/jats:italic> within the chromosomal radC<\/jats:italic> gene. The mec<\/jats:italic>A<\/jats:styled-content>\u2010positive S<\/jats:styled-content>.\u00a0pseudintermedius <\/jats:italic>ST<\/jats:styled-content>68 strain was also multidrug resistant and harboured the erm<\/jats:italic>(B<\/jats:styled-content>)\u2010T<\/jats:styled-content>n5405<\/jats:italic>\u2010like element. This ST<\/jats:styled-content>68 strain presented a clear susceptible phenotype to oxacillin and cefoxitin regardless of the presence of an integral and conserved mec<\/jats:italic>A<\/jats:styled-content> gene and mecA<\/jats:italic> promoter, which enhances the need for testing the presence of this gene in routine analysis to avoid treatment failures. These data reflect the extended anti\u2010microbial resistance gene acquisition capacities of both bacterial species and evidence their pathogenic properties. The first detection of MRSA ST<\/jats:styled-content>398 and S<\/jats:styled-content>.\u00a0pseudintermedius <\/jats:italic>ST<\/jats:styled-content>68 in horses in S<\/jats:styled-content>pain is reported.<\/jats:p>","DOI":"10.1111\/zph.12059","type":"journal-article","created":{"date-parts":[[2013,6,17]],"date-time":"2013-06-17T07:35:26Z","timestamp":1371454526000},"page":"192-201","source":"Crossref","is-referenced-by-count":24,"title":["First Detection of M<\/scp>ethicillin\u2010R<\/scp>esistant S<\/scp>taphylococcus aureus <\/i>ST<\/scp>398 and S<\/scp>taphylococcus pseudintermedius <\/i>ST<\/scp>68 from Hospitalized Equines in S<\/scp>pain"],"prefix":"10.1111","volume":"61","author":[{"given":"E.","family":"G\u00f3mez\u2010Sanz","sequence":"first","affiliation":[{"name":"Area Bioqu\u00edmica y Biolog\u00eda Molecular Universidad de La Rioja Logro\u00f1o Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Sim\u00f3n","sequence":"additional","affiliation":[{"name":"Departamento de Patolog\u00eda Animal Facultad de Veterinaria Universidad de Zaragoza Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ortega","sequence":"additional","affiliation":[{"name":"Departamento de Patolog\u00eda Animal Facultad de Veterinaria Universidad de Zaragoza Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"G\u00f3mez","sequence":"additional","affiliation":[{"name":"Area Bioqu\u00edmica y Biolog\u00eda Molecular Universidad de La Rioja Logro\u00f1o Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Lozano","sequence":"additional","affiliation":[{"name":"Area Bioqu\u00edmica y Biolog\u00eda Molecular Universidad de La Rioja Logro\u00f1o Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Zarazaga","sequence":"additional","affiliation":[{"name":"Area Bioqu\u00edmica y Biolog\u00eda Molecular Universidad de La Rioja Logro\u00f1o Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Torres","sequence":"additional","affiliation":[{"name":"Area Bioqu\u00edmica y Biolog\u00eda Molecular Universidad de La Rioja Logro\u00f1o Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,6,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01150-07"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01915-08"},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.4315\/0362-028X-67.10.2302","article-title":"Development of a PCR test to differentiate between Staphylococcus aureus and Staphylococcus intermedius","volume":"67","author":"Baron F.","year":"2004","journal-title":"J. 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