{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:48:12Z","timestamp":1788691692678,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,3,27]],"date-time":"2014-03-27T00:00:00Z","timestamp":1395878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>This article describes and contrasts the public health response to two human rabies cases: one organ recipient diagnosed within days of symptom onset and the transplant donor who was diagnosed 18\u00a0months post\u2010symptom onset. In response to an organ\u2010transplant\u2010related rabies case diagnosed in 2013, organ donor and recipient investigations were conducted by multiple public health agencies. Persons with potential exposure to infectious patient materials were assessed for rabies virus exposure. An exposure investigation was conducted to determine the source of the organ donor's infection. Over 100 persons from more than 20 agencies spent over 2700\u00a0h conducting contact investigations in healthcare, military and community settings. The 564 persons assessed include 417 healthcare workers [5.8% recommended for post\u2010exposure prophylaxis (<jats:styled-content style=\"fixed-case\">PEP<\/jats:styled-content>)], 96 community contacts (15.6% recommended for <jats:styled-content style=\"fixed-case\">PEP<\/jats:styled-content>), 30 autopsy personnel (50% recommended for <jats:styled-content style=\"fixed-case\">PEP<\/jats:styled-content>), and 21 other persons (4.8% recommended for <jats:styled-content style=\"fixed-case\">PEP<\/jats:styled-content>). Donor contacts represented 188 assessed with 20.2% recommended for <jats:styled-content style=\"fixed-case\">PEP<\/jats:styled-content>, compared with 5.6% of 306 recipient contacts recommended for <jats:styled-content style=\"fixed-case\">PEP<\/jats:styled-content>. Human rabies cases result in substantial use of public health and medical resources, especially when diagnosis is delayed. Although rare, clinicians should consider rabies in cases of encephalitis of unexplained aetiology, particularly for cases that may result in organ donation.<\/jats:p>","DOI":"10.1111\/zph.12105","type":"journal-article","created":{"date-parts":[[2014,3,27]],"date-time":"2014-03-27T07:49:18Z","timestamp":1395906558000},"page":"560-570","source":"Crossref","is-referenced-by-count":20,"title":["A Large\u2010scale, Rapid Public Health Response to Rabies in an Organ Recipient and the Previously Undiagnosed Organ Donor"],"prefix":"10.1111","volume":"61","author":[{"given":"R. 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